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Review: could Plaquenil cause Fatigue?

Summary: Fatigue is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Methotrexate, and have Rheumatoid arthritis.

We study 14,739 people who have side effects while taking Plaquenil from FDA and social media. Among them, 959 have Fatigue. Find out below who they are, when they have Fatigue and more.

You are not alone: join a mobile support group for people who take Plaquenil and have Fatigue >>>

 

 

 

 

Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. (latest outcomes from 15,547 Plaquenil users)

Fatigue

Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis. (latest reports from 200,846 Fatigue patients)

On Feb, 3, 2015: 14,723 people reported to have side effects when taking Plaquenil. Among them, 961 people (6.53%) have Fatigue.

Trend of Fatigue in Plaquenil reports

Time on Plaquenil when people have Fatigue * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Fatigue18.29%17.07%13.41%18.29%14.63%12.20%6.10%

Gender of people who have Fatigue when taking Plaquenil * :

FemaleMale
Fatigue86.38%13.62%

Age of people who have Fatigue when taking Plaquenil * :

0-12-910-1920-2930-3940-4950-5960+
Fatigue0.00%0.00%1.19%3.21%9.27%18.55%30.56%37.22%

Severity of Fatigue when taking Plaquenil ** :

leastmoderateseveremost severe
Fatigue3.92%43.14%45.10%7.84%

How people recovered from Fatigue ** :

while on the drugafter off the drugnot yet
Fatigue0.00%20.00%80.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (404 people, 42.04%)
  2. Osteoporosis (143 people, 14.88%)
  3. Systemic lupus erythematosus (136 people, 14.15%)
  4. Pain (58 people, 6.04%)
  5. Hypertension (56 people, 5.83%)

Top co-used drugs for these people * :

  1. Methotrexate (295 people, 30.70%)
  2. Prednisone (260 people, 27.06%)
  3. Enbrel (244 people, 25.39%)
  4. Folic acid (190 people, 19.77%)
  5. Aspirin (122 people, 12.70%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of plaquenil and fatigue on

Do you have Fatigue while taking Plaquenil?

You are not alone! Join a mobile support group:
- support group for people who take Plaquenil and have Fatigue
- support group for people who take Plaquenil
- support group for people who have Fatigue

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    ringing in ears caused by temazepam.
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  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Diagnosed with postural orthostatic tachycardia syndrome after mirena
    After getting the Mirena put in, I got really sick. I went home and got super dizzy, nauseous, and tired. I felt so sick and could barely function. I called the doctors office and they said it couldn't be from the Mirena. She said that I must have the flu. Well, I kept it in for a little while longer. I then started losing my hair. I went back into my doctors office because they thought I was experiencing the symptoms for the Mirena going through my uterine wall. The ultra sound was fine. She reassured me that the Mirena could not be the cause of my complications. So, a week a later I went to another doctor to have the Mirena taken out.
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  • Mucinex dm and advil congetstion
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More reviews for: Plaquenil, Fatigue

Comments from related studies:

  • From this study (4 months ago):

  • have had a swollen arm now for 10 months. Measures 7 cm more than right arm. Now swelling is also in forearm. Have had lymp test for blockages. No blockages found. Now starting to get same symptoms in right knee. have been diagnosed with palandromic rheumatoid for 2 years now. Positive RF 82 IU/ml. ESR 31. CRP 22mg/L.25-OH Vitamin D L12.

    Reply

  • From this study (8 months ago):

  • Sjogren's Syndrome

    Reply

  • From this study (9 months ago):

  • Severe fatigue 2 weeks after starting plaquenil

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