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Review: could Plaquenil cause Fatigue?

Summary: Fatigue could be caused by Plaquenil, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take Methotrexate, and have Rheumatoid arthritis.

We study 14,631 people who have side effects while taking Plaquenil from FDA and social media. Among them, 951 have Fatigue. Find out below who they are, when they have Fatigue and more.

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Plaquenil

Plaquenil (latest outcomes from 15,430 users) has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus.

Fatigue

Fatigue (feeling of tiredness) (latest reports from 1,536,668 patients) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.

On Apr, 12, 2014: 14,665 people reported to have side effects when taking Plaquenil. Among them, 951 people (6.48%) have Fatigue. They amount to 0.06% of all the 1,535,917 people who have Fatigue on eHealthMe.

Trend of Fatigue in Plaquenil reports

Time on Plaquenil when people have Fatigue * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Fatigue20.83%15.28%12.50%19.44%12.50%13.89%5.56%

Gender of people who have Fatigue when taking Plaquenil * :

FemaleMale
Fatigue86.24%13.76%

Age of people who have Fatigue when taking Plaquenil * :

0-12-910-1920-2930-3940-4950-5960+
Fatigue0.00%0.00%1.20%3.25%9.03%18.41%30.69%37.42%

Severity of Fatigue when taking Plaquenil ** :

leastmoderateseveremost severe
Fatigue4.88%36.59%48.78%9.76%

How people recovered from Fatigue ** :

while on the drugafter off the drugnot yet
Fatigue0.00%16.67%83.33%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (400 people, 42.06%)
  2. Osteoporosis (143 people, 15.04%)
  3. Systemic lupus erythematosus (136 people, 14.30%)
  4. Pain (57 people, 5.99%)
  5. Hypertension (56 people, 5.89%)

Top co-used drugs for these people * :

  1. Methotrexate (293 people, 30.81%)
  2. Prednisone (259 people, 27.23%)
  3. Enbrel (243 people, 25.55%)
  4. Folic acid (189 people, 19.87%)
  5. Aspirin (122 people, 12.83%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Plaquenil, Fatigue

You can also:

On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used for systemic lupus erythematosus. Find out below the conditions Plaquenil is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Plaquenil used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

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