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Review: could Plaquenil cause Nausea?

Summary: Nausea could be caused by Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take Methotrexate, and have Rheumatoid arthritis.

We study 14,631 people who have side effects while taking Plaquenil from FDA and social media. Among them, 1,009 have Nausea. Find out below who they are, when they have Nausea and more.

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Plaquenil

Plaquenil (latest outcomes from 15,430 users) has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus.

Nausea

Nausea (feeling of having an urge to vomit) (latest reports from 1,909,097 patients) has been reported by people with type 2 diabetes, high blood pressure, quit smoking, depression, pain.

On Apr, 13, 2014: 14,665 people reported to have side effects when taking Plaquenil. Among them, 1,009 people (6.88%) have Nausea. They amount to 0.05% of all the 1,907,838 people who have Nausea on eHealthMe.

Trend of Nausea in Plaquenil reports

Time on Plaquenil when people have Nausea * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Nausea20.55%17.81%6.85%30.14%12.33%8.22%4.11%

Gender of people who have Nausea when taking Plaquenil * :

FemaleMale
Nausea89.74%10.26%

Age of people who have Nausea when taking Plaquenil * :

0-12-910-1920-2930-3940-4950-5960+
Nausea0.00%0.00%0.90%6.30%11.36%20.70%28.01%32.73%

Severity of Nausea when taking Plaquenil ** :

leastmoderateseveremost severe
Nausea4.55%72.73%18.18%4.55%

How people recovered from Nausea ** :

while on the drugafter off the drugnot yet
Nausea13.33%26.67%60.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (320 people, 31.71%)
  2. Systemic lupus erythematosus (144 people, 14.27%)
  3. Osteoporosis (108 people, 10.70%)
  4. Hypertension (56 people, 5.55%)
  5. Pain (43 people, 4.26%)

Top co-used drugs for these people * :

  1. Methotrexate (320 people, 31.71%)
  2. Prednisone (256 people, 25.37%)
  3. Folic acid (218 people, 21.61%)
  4. Enbrel (184 people, 18.24%)
  5. Nexium (114 people, 11.30%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Plaquenil, Nausea

You can also:

On eHealthMe, Plaquenil (hydroxychloroquine sulfate) is often used for systemic lupus erythematosus. Find out below the conditions Plaquenil is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Plaquenil used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 months ago):

  • 2+ Urine samples with moderate amount of blood(hysterectomy 2 yrs ago) and more than 2 UA's with protein in my urine. Last UA result was 30+ protein in urine. Personal History of kidney stones 10+yrs and Family hX of kidney problemss.

    Reply

  • From this study (7 months ago):

  • Was diagnosed with SLE and Lupus Nephritis Dec 2012, I was on prednisone for 9 months, completely off a month ago. Cellcept since Dec 2012, lisinopril and plaquenil since around feb 2013.

    Started getting difficulty swallowing and nausea that comes and goes (not necessarily at the same time) about 2 months ago when I was on 5mg of prednisone and chalked it up to tapering side effects. No longer on prednisone, nausea has continued, Dr. put me on Ranitidine 2 weeks ago and the horrible gagging everytime I swallowed subsided, but it's still difficult to swallow a lot of the time (food, not saliva, drink, or even pills.) It seems to get worse randomly after I eat, but I'm wondering if it's not just stomach acid but something bigger.

    Rheumatologist told me that putting me on a PPI might be the next course of action rather than Ranitidine because PPIs promote the healing of injuries caused by stomach acid, but I'm wondering if I need to go see a GI about this since I let it go unchecked for so long.

    Reply

  • From this study (1 year ago):

  • Newly diagnosed RA and Fibro. Post cervical spine fusion syndrome. Osteoarthritis Degenerative osteoarthritis. Starting to have moments of falling asleep. High stress job in hostile environment. Concerns about mortgage.

    Reply

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