Review: could Prednisone cause Knee Joint Replacement?


Knee joint replacement is found among people who take Prednisone, especially for people who are female, 60+ old , have been taking the drug for 10+ years, also take medication Methotrexate, and have Rheumatoid arthritis . We study 139,345 people who have side effects while taking Prednisone from FDA and social media. Among them, 252 have Knee joint replacement. Find out below who they are, when they have Knee joint replacement and more.

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Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. (latest outcomes from Prednisone 231,563 users)

Knee Joint Replacement

Knee joint replacement has been reported by people with rheumatoid arthritis, multiple sclerosis, osteoporosis, high blood pressure, pain (latest reports from 10,810 Knee joint replacement patients).

On Oct, 21, 2016

139,345 people reported to have side effects when taking Prednisone.
Among them, 252 people (0.18%) have Knee Joint Replacement

Number of reports submitted per year:

Could Prednisone cause Knee joint replacement?

Time on Prednisone when people have Knee Joint Replacement *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 66.67 %

Gender of people who have Knee Joint Replacement when taking Prednisone *:

  • female: 76.42 %
  • male: 23.58 %

Age of people who have Knee Joint Replacement when taking Prednisone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.52 %
  • 40-49: 15.25 %
  • 50-59: 27.12 %
  • 60+: 53.11 %

Top conditions involved for these people *:

  • Rheumatoid Arthritis (133 people, 52.78%)
  • Osteoporosis (39 people, 15.48%)
  • Hypertension (32 people, 12.70%)
  • Pain (24 people, 9.52%)
  • Depression (12 people, 4.76%)

Top co-used drugs for these people *:

  • Methotrexate (91 people, 36.11%)
  • Enbrel (64 people, 25.40%)
  • Humira (62 people, 24.60%)
  • Folic Acid (54 people, 21.43%)
  • Remicade (49 people, 19.44%)

Top other side effects for these people *:

  • Pain (49 people, 19.44%)
  • Osteoarthritis (45 people, 17.86%)
  • Arthralgia (38 people, 15.08%)
  • Back Pain (35 people, 13.89%)
  • Fall (34 people, 13.49%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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