Review: could Prednisone cause Mental Status Changes?


Mental status changes is found among people who take Prednisone, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Zometa, and have Pain . We study 139,347 people who have side effects while taking Prednisone from FDA and social media. Among them, 751 have Mental status changes. Find out below who they are, when they have Mental status changes and more.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. (latest outcomes from Prednisone 231,563 users)

Mental Status Changes

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation) has been reported by people with pain, depression, high blood pressure, multiple myeloma, multiple sclerosis (latest reports from 19,524 Mental status changes patients).

On Oct, 22, 2016

139,347 people reported to have side effects when taking Prednisone.
Among them, 751 people (0.54%) have Mental Status Changes

Number of reports submitted per year:

Could Prednisone cause Mental status changes?

Time on Prednisone when people have Mental Status Changes *:

  • < 1 month: 64.71 %
  • 1 - 6 months: 19.61 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 11.76 %
  • 2 - 5 years: 1.96 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 1.96 %

Gender of people who have Mental Status Changes when taking Prednisone *:

  • female: 51.36 %
  • male: 48.64 %

Age of people who have Mental Status Changes when taking Prednisone *:

  • 0-1: 0.0 %
  • 2-9: 1.08 %
  • 10-19: 2.93 %
  • 20-29: 1.54 %
  • 30-39: 2.31 %
  • 40-49: 11.56 %
  • 50-59: 19.11 %
  • 60+: 61.48 %

Top conditions involved for these people *:

  • Pain (76 people, 10.12%)
  • Multiple Myeloma (62 people, 8.26%)
  • Renal Transplant (44 people, 5.86%)
  • Rheumatoid Arthritis (42 people, 5.59%)
  • Osteoporosis (35 people, 4.66%)

Top co-used drugs for these people *:

  • Zometa (172 people, 22.90%)
  • Lasix (142 people, 18.91%)
  • Aspirin (140 people, 18.64%)
  • Aredia (117 people, 15.58%)
  • Folic Acid (112 people, 14.91%)

Top other side effects for these people *:

  • Anxiety (213 people, 28.36%)
  • Pain (202 people, 26.90%)
  • Asthenia (202 people, 26.90%)
  • Confusional State (197 people, 26.23%)
  • Pyrexia (185 people, 24.63%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Mental status changes when taking Prednisone?

Browse all side effects of Prednisone

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Mental status changes

Mental status changes

Could your condition cause Mental status changes

Mental status changes

Related studies

Can you answer these questions?

More questions for: Prednisone, Mental status changes

You may be interested in these reviews

More reviews for: Prednisone, Mental status changes

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.