Review: could Prempro cause Breast Cancer?


Summary

Breast cancer is found among people who take Prempro, especially for people who are female, 50-59 old , have been taking the drug for 2 - 5 years, also take medication Premarin, and have Hormone replacement therapy . We study 39,059 people who have side effects while taking Prempro from FDA and social media. Among them, 14,669 have Breast cancer. Find out below who they are, when they have Breast cancer and more.

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Prempro

Prempro has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in hormone replacement therapy. (latest outcomes from Prempro 39,542 users)

Breast Cancer

Breast cancer has been reported by people with breathing difficulty, death, rashes, diarrhea, joint pain (latest reports from 103,129 Breast cancer patients).

On Sep, 16, 2016

39,059 people reported to have side effects when taking Prempro.
Among them, 14,669 people (37.56%) have Breast Cancer


Number of reports submitted per year:

Could Prempro cause Breast cancer?

Time on Prempro when people have Breast Cancer *:

  • < 1 month: 0.56 %
  • 1 - 6 months: 2.46 %
  • 6 - 12 months: 3.12 %
  • 1 - 2 years: 11.42 %
  • 2 - 5 years: 37.75 %
  • 5 - 10 years: 33.33 %
  • 10+ years: 11.35 %

Gender of people who have Breast Cancer when taking Prempro *:

  • female: 99.92 %
  • male: 0.08 %

Age of people who have Breast Cancer when taking Prempro *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.01 %
  • 30-39: 0.13 %
  • 40-49: 5.72 %
  • 50-59: 50.9 %
  • 60+: 43.24 %

Top conditions involved for these people *:

  • Hormone Replacement Therapy (7,139 people, 48.67%)
  • Menopausal Symptoms (845 people, 5.76%)
  • Oestrogen Replacement Therapy (565 people, 3.85%)
  • Menopause (373 people, 2.54%)
  • Hypertension (179 people, 1.22%)

Top co-used drugs for these people *:

  • Premarin (9,220 people, 62.85%)
  • Provera (8,231 people, 56.11%)
  • Cycrin (1,828 people, 12.46%)
  • Medroxyprogesterone Acetate (1,656 people, 11.29%)
  • Estrace (1,070 people, 7.29%)

Top other side effects for these people *:

  • Oestrogen Receptor Assay Positive (187 people, 1.27%)
  • Progesterone Receptor Assay Positive (151 people, 1.03%)
  • Depression (139 people, 0.95%)
  • Mastectomy (138 people, 0.94%)
  • Anxiety (128 people, 0.87%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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