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Review: could Prempro cause Breast cancer?

We study 37,484 people who have side effects while taking Prempro from FDA and social media. Among them, 14,615 have Breast cancer. Find out below who they are, when they have Breast cancer and more.

Get connected: join a mobile support group for people who take Prempro and have Breast cancer >>>


Prempro (latest outcomes from 37,628 users) has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. It is often used in menopause.

Breast cancer

Breast cancer (latest reports from 197,929 patients) has been reported by people with hormone replacement therapy, multiple sclerosis, rheumatoid arthritis, menopausal symptoms, osteoporosis.

On Sep, 18, 2014: 37,484 people reported to have side effects when taking Prempro. Among them, 14,615 people (38.99%) have Breast Cancer.

Trend of Breast cancer in Prempro reports

Time on Prempro when people have Breast cancer * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Breast cancer0.55%2.44%3.78%12.28%35.88%33.57%11.49%

Age of people who have Breast cancer when taking Prempro * :

Breast cancer0.00%0.00%0.00%0.01%0.12%5.90%51.04%42.94%

Severity of Breast cancer when taking Prempro ** :


How people recovered from Breast cancer ** :


Top conditions involved for these people * :

  1. Hormone replacement therapy (7,440 people, 50.91%)
  2. Menopausal symptoms (975 people, 6.67%)
  3. Menopause (474 people, 3.24%)
  4. Hypertension (227 people, 1.55%)
  5. Hot flush (142 people, 0.97%)

Top co-used drugs for these people * :

  1. Premarin (9,602 people, 65.70%)
  2. Provera (8,537 people, 58.41%)
  3. Cycrin (1,849 people, 12.65%)
  4. Medroxyprogesterone acetate (1,702 people, 11.65%)
  5. Estrace (1,125 people, 7.70%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Breast Cancer while taking Prempro?

Get connected! Join a mobile support group:
- support group for people who take Prempro and have Breast Cancer
- support group for people who take Prempro
- support group for people who have Breast Cancer

Comments from related studies:

  • From this study (3 years ago):

  • Judy on Jul, 4, 2011:

    I have been taking prometrium for two weeks now. It has helped reduce my headaches and I sleep so much better. The one negative thing I've noticed is my varicose veins in the back of my calf are protruding more and are painful. They used to be painful when I was having periods or if I was on birth control pills, but I haven't had a period in two years now and the varicose veins didn't give me any problems. But now with the prometrium I'm feeling it again. Is it not safe for me to take prometrium because of the varicose veins?


Can you answer these questions (what is this?):

More questions for: Prempro, Breast cancer

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More reviews for: Prempro, Breast cancer

On eHealthMe, Prempro (estrogens, conjugated; medroxyprogesterone acetate) is often used for menopause. Find out below the conditions Prempro is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Prempro used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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