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Review: could Prilosec cause High blood pressure?

Summary: High blood pressure is found among people who take Prilosec, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Vioxx, and have High blood pressure.

We study 59,777 people who have side effects while taking Prilosec from FDA and social media. Among them, 2,952 have High blood pressure. Find out below who they are, when they have High blood pressure and more.

You are not alone: join a support group for people who take Prilosec and have High blood pressure >>>



Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. (latest outcomes from 61,552 Prilosec users)

High blood pressure

High blood pressure has been reported by people with osteoporosis, depression, multiple sclerosis, pain, rheumatoid arthritis. (latest reports from 329,841 High blood pressure patients)

On Apr, 13, 2015: 59,777 people reported to have side effects when taking Prilosec. Among them, 2,952 people (4.94%) have High Blood Pressure.

Trend of High blood pressure in Prilosec reports

Time on Prilosec when people have High blood pressure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
High blood pressure20.34%30.51%6.78%6.78%13.56%15.25%6.78%

Gender of people who have High blood pressure when taking Prilosec * :

High blood pressure65.60%34.40%

Age of people who have High blood pressure when taking Prilosec * :

High blood pressure0.15%0.23%0.15%1.32%4.41%11.88%29.71%52.15%

Severity of High blood pressure when taking Prilosec ** :

leastmoderateseveremost severe
High blood pressure0.00%75.00%25.00%0.00%

How people recovered from High blood pressure ** :

while on the drugafter off the drugnot yet
High blood pressure0.00%66.67%33.33%

Top conditions involved for these people * :

  1. Hypertension (352 people, 11.92%)
  2. Gastrooesophageal reflux disease (350 people, 11.86%)
  3. Pain (304 people, 10.30%)
  4. Osteoporosis (257 people, 8.71%)
  5. Depression (191 people, 6.47%)

Top co-used drugs for these people * :

  1. Vioxx (733 people, 24.83%)
  2. Aspirin (710 people, 24.05%)
  3. Lipitor (536 people, 18.16%)
  4. Lasix (479 people, 16.23%)
  5. Zometa (435 people, 14.74%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of prilosec and high blood pressure on

Do you have High Blood Pressure while taking Prilosec?




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- support group for people who take Prilosec and have High Blood Pressure
- support group for people who take Prilosec
- support group for people who have High Blood Pressure

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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