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Review: could Prilosec cause High blood pressure?

Summary: High blood pressure could be caused by Prilosec, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Vioxx, and have Hypertension.

We study 59,677 people who have side effects while taking Prilosec from FDA and social media. Among them, 2,957 have High blood pressure. Find out below who they are, when they have High blood pressure and more.

On Apr, 10, 2014: 59,664 people reported to have side effects when taking Prilosec. Among them, 2,957 people (4.96%) have High Blood Pressure. They amount to 0.26% of all the 1,139,537 people who have High Blood Pressure on eHealthMe.

Trend of High blood pressure in Prilosec reports

Time on Prilosec when people have High blood pressure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
High blood pressure19.67%34.43%6.56%6.56%13.11%14.75%4.92%

Gender of people who have High blood pressure when taking Prilosec * :

High blood pressure65.53%34.47%

Age of people who have High blood pressure when taking Prilosec * :

High blood pressure0.15%0.23%0.19%1.32%4.40%11.92%29.81%51.99%

Severity of High blood pressure when taking Prilosec ** :

leastmoderateseveremost severe
High blood pressure0.00%50.00%50.00%0.00%

How people recovered from High blood pressure ** :

while on the drugafter off the drugnot yet
High blood pressure0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Hypertension (352 people, 11.90%)
  2. Gastrooesophageal reflux disease (350 people, 11.84%)
  3. Pain (304 people, 10.28%)
  4. Osteoporosis (257 people, 8.69%)
  5. Depression (191 people, 6.46%)

Top co-used drugs for these people * :

  1. Vioxx (734 people, 24.82%)
  2. Aspirin (710 people, 24.01%)
  3. Lipitor (536 people, 18.13%)
  4. Lasix (479 people, 16.20%)
  5. Zometa (437 people, 14.78%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Prilosec, High blood pressure

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On eHealthMe, Prilosec (omeprazole) is often used for gastroesophageal reflux disease. Find out below the conditions Prilosec is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Prilosec used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 months ago):

  • Depression, moderate Hypertension not controlled yet. Joint pain... Shoulder Osteoarthritis worth necrosis and bone spurs. New shoulder with in the next 5 years.


  • From this study (5 months ago):

  • Increase has been during several surgeries and recovery periods


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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- Prilosec side effects


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- High Blood Pressure



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