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Review: could Progesterone cause Anxiety (Stress and anxiety)?

Summary: Anxiety is found among people who take Progesterone, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take medication Premarin, and have Depression.

We study 4,304 people who have side effects while taking Progesterone from FDA and social media. Among them, 160 have Anxiety. Find out below who they are, when they have Anxiety and more.

You are not alone: join a mobile support group for people who take Progesterone and have Anxiety >>>

 

 

 

 

Progesterone

Progesterone has active ingredients of progesterone. It is often used in hormone replacement therapy. (latest outcomes from 4,485 Progesterone users)

Anxiety

Anxiety has been reported by people with depression, stress and anxiety, quit smoking, multiple sclerosis, pain. (latest reports from 212,462 Anxiety patients)

On Jan, 1, 2015: 4,299 people reported to have side effects when taking Progesterone. Among them, 197 people (4.58%) have Anxiety.

Trend of Anxiety in Progesterone reports

Time on Progesterone when people have Anxiety * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anxiety7.14%21.43%7.14%0.00%28.57%14.29%21.43%

Age of people who have Anxiety when taking Progesterone * :

0-12-910-1920-2930-3940-4950-5960+
Anxiety1.12%0.00%1.69%8.43%16.29%24.16%33.15%15.17%

Severity of Anxiety when taking Progesterone ** :

leastmoderateseveremost severe
Anxiety0.00%33.33%50.00%16.67%

How people recovered from Anxiety ** :

while on the drugafter off the drugnot yet
Anxiety0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (24 people, 12.18%)
  2. Anxiety (23 people, 11.68%)
  3. Hormone replacement therapy (19 people, 9.64%)
  4. Menopausal symptoms (15 people, 7.61%)
  5. Sleep disorder (13 people, 6.60%)

Top co-used drugs for these people * :

  1. Premarin (38 people, 19.29%)
  2. Estradiol (27 people, 13.71%)
  3. Estrace (25 people, 12.69%)
  4. Fosamax (23 people, 11.68%)
  5. Prozac (21 people, 10.66%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Anxiety while taking Progesterone?

You are not alone! Join a mobile support group:
- support group for people who take Progesterone and have Anxiety
- support group for people who take Progesterone
- support group for people who have Anxiety

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More questions for: Progesterone, Anxiety

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    Then a different ob/gyn suggested I try progesterone only. He prescribed a pink round ball of a pill. I was to take it the last 10 days of the month. I tried that for 3 or 4 months, it wasn't making things better... in fact I think it made it worse. Then I went cold turkey again for the better part of a year. At age 37, after not finding a doctor that was helping the situation I decided to find a doctor in AZ. I live full time in CA but had a vacation home in AZ so I thought I'd try that for a change.

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    None of my issues were solved. I had stopped taking the yaz or any birth control at that point. My period were non existent after boiling my uterus in boiling water, which is what the ablation is. And to this day my period is hardly worth talking about or being prepared for. It's spotting for a couple 3 days at best. With regard to my symptoms, the pms, pmdd, extreme irritability, depression all that stayed the same. I tried Seasonal for about 2 months and that was not good, it seemed to 'amp' the 'hot' - not physically hot but an irritable term I use to describe the upped level my nerves set at.

    I did exercise pretty regularly during all if this. The times I wasn't exercising were over the top as far as pmdd symptoms so that motivates you to get your rear to the gym. On the Yaz 24 day I knew something wasn't right. At day 14 I'd feel the symptoms if ovulation, not imagined but real. I was slightly irritable and had cramps for 2 to 3 days. At day 17, a Wednesday the irritability would ramp up and the depression would start to be present for the next 2 weeks.

    The following Wednesday was day 24, that was the last day of taking the pill. I did get a bit of relief after stopping the pill and 4 days later I resumed taking the next months pack on Sunday. The thing is I wouldn't get my period until Tuesday after I started the new pack? I know that my period should have happened between day 24 and 28 but it never did. It always started on day 31 or 32 and lasted 2 to 3 days. Then the whole cycle begins again with day 14.

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    Day 1 Sunday
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    The ob/gyn expertise wasn't working, male or female. I went to my regular general practitioner for a check up and had done much research on the type of hormones in the Yaz, Yasmin and many others. I was convinced that I need to move over to Yasmin 21 day. It had a but more estrogen and it was only 21 instead of 24 days so worth a try.

    She asked me when the last time I felt 'normal' with regard to the hormones. I told her that as far as I can recall it was when I was in my 20's when I was taking the Ortho Novum 777. She said why don't we have you start taking that again! I was like, what? I explained I was told I could not take that because of my age and I thought some doctor had told me it had been discontinued years ago anyway. She said no, I can prescribe it to you, it's still available. I was a little excited about that. Maybe... just maybe that would be a solution for relief. My blood pressure is 100/70 always has been low, I don't smoke and I'm 5' 8", 150 pounds. She saw no reason for me not to try it again. We agreed that I would and if it didn't go well we'd try the Yasmin.

    I've been in the Ortho Novum, my package and brand saying Alyacen 7/7/7 for 3 weeks now. Today is Sunday and I stop taking active pills for 7 days now. At day 7 or so I noticed how much easier it was becoming to get out of bed in the morning. I began noticing I had an interest in getting something done. I didn't have a big heavy cloud urging me to just stay in bed. I started feeling alive again.

    The jury is still out and I have ordered a second months supply but I am deeply encouraged. During week 3 I have been crampier than on the yaz but in a very normal feeling way. Like my body is preparing for menstruation. I'm anticipating bleeding heavier than I'm used to, but in a good way. The cramping has been something I definitely notice much much more so but it's manageable. What I also notice is lack...... huge overwhelming lack of that horrible irritability. I'm more sensitive than weeks one and two but it's nothing by comparison. I've been more level headed, more 'normal'. Time will tell if this is my cure for the next 6 or so years but I'm extremely encouraged right now. I literally feel the best I have in years and there is some pretty crapy stressful things going on in my life. But I can handle them-

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    God Bless
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Comments from related studies:

  • From this study (4 months ago):

  • I started losing my hair more when I started taking the tramadol for pain. I have lost quite a bit of hair since then and started balding on the top of my head. I don't know if it is hormonal or from all the medication I am on because I know that can cause hair loss also. My hair is also limp and lifeless and I have gained about 15 pounds since being on the tramadol. It is the only medication that helps with my pain and chronic anxiety caused by the Cymbalta so I don't know what else to do.

    Reply

    axeman225 on Sep, 17, 2014:

    Hi! I am a 26yr old male. I saw this and seems like we are taking the same meds and I wanted to compare. I have been on tramadol for almost 3 years for herniated discs from playing football. I recently have noticed and heard that long term use affects testosterone levels, so I got bloodwork done...turns out I am below range on all levels...which sucks because I am fit (or was) and pretty big. So my doc prescribed testim 1% 50mg/day (as of yesterday) and I wanted to see how it affected you along with takign the tramadol. I dont have hair issues, but I have had weight gain and general feminization due to loss of testosterone....so gross and sad for me. Idk if you are male or female...but I would love to hear what the combo has done for you. If anyone else can chime in it would be great. (fyi..tramadol is a low dose opiate agonist for pain; testim is testosterone gel)

    Reply

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