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Review: could Progesterone cause Weight gain (Weight increased)?

Summary: Weight gain is found among people who take Progesterone, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Calcium, and have Depression.

We study 4,310 people who have side effects while taking Progesterone from FDA and social media. Among them, 102 have Weight gain. Find out below who they are, when they have Weight gain and more.

You are not alone: join a mobile support group for people who take Progesterone and have Weight gain >>>

 

 

 

 

Progesterone

Progesterone has active ingredients of progesterone. It is often used in menopause. (latest outcomes from 4,492 Progesterone users)

Weight gain

Weight gain has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol. (latest reports from 76,592 Weight gain patients)

On Feb, 1, 2015: 4,304 people reported to have side effects when taking Progesterone. Among them, 102 people (2.37%) have Weight Gain.

Trend of Weight gain in Progesterone reports

Time on Progesterone when people have Weight gain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Weight gain0.00%22.22%33.33%0.00%33.33%0.00%11.11%

Age of people who have Weight gain when taking Progesterone * :

0-12-910-1920-2930-3940-4950-5960+
Weight gain0.00%0.00%0.00%6.90%16.09%20.69%44.83%11.49%

Severity of Weight gain when taking Progesterone ** :

leastmoderateseveremost severe
Weight gain14.29%28.57%42.86%14.29%

How people recovered from Weight gain ** :

while on the drugafter off the drugnot yet
Weight gain0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Depression (16 people, 15.69%)
  2. Hypothyroidism (6 people, 5.88%)
  3. Hormone replacement therapy (6 people, 5.88%)
  4. Pain (5 people, 4.90%)
  5. Rheumatoid arthritis (5 people, 4.90%)

Top co-used drugs for these people * :

  1. Calcium (13 people, 12.75%)
  2. Estradiol (12 people, 11.76%)
  3. Humira (11 people, 10.78%)
  4. Premarin (11 people, 10.78%)
  5. Enbrel (9 people, 8.82%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Weight Gain while taking Progesterone?

You are not alone! Join a mobile support group:
- support group for people who take Progesterone and have Weight Gain
- support group for people who take Progesterone
- support group for people who have Weight Gain

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More questions for: Progesterone, Weight gain

You may be interested at these reviews (Write a review):

  • Complera weight gain
    Switched from Atripla to Complera about 4 months ago due to neuronal toxicity. Started Complera and gained over twenty pounds in a month and continue to gain. I have always been thin with a very high metabolism. Now I have to watch ever single thing I eat.
  • Terbinafine hydrochloride
    I would not reccomend this at all. I was described this drug 6months ago. Bad side effects still ongoing rapid weight gain and water retention in putting on 2 stone in less than 6months. No menstrual in ya year Bloatingin the face arms legs and gut. Been to the doctors said nothing can be done so how much longer can you put up with ffeeling like this.should not be prescribed. Makes you feel dreadfull.
  • Yaz was the cause of increasing my pmdd, pms, irritability and depression symptoms
    I had taken Ortho Novum 777 from the age of 18 to 28 stopping in-between pregnancies. I had 3 children between the ages of 21 and 29.

    In my early 30's I decided to stop taking birth control pills simply because I 'thought' it would be a healthier thing to do for my body. I did know that unless I was taking Ortho Novum that my period were not the standard 28 day routine. They were irregular and would be anywhere from 28 to 38 days. The longer the time in between periods the worse the pms symptoms would be. My theory is most likely because of the extended time between when I perceived a period and when I actually got it. It could very well have been psychosomatic but when my period would finally arrive, irritability and bloating would subside within a day or two. It was like a reset button and relief. I was calmer, more rational, even Kiel and motivated.

    In addition to the irregular pattern of my periods when off if birth control pills I also experienced pms twice a month. It would happen mid month when I was ovulating. The ovulation would be uncomfortable, I'd feel bloated again, and the cramps were painful. I'd move from ovulation week of irritability to PMS week of even greater irritability. I'd be waiting and counting down til my period was suppose to happen in anticipation of relief.

    I remember age 32 being significant for some reason. Upon reflecting back over the years while seeking treatment for a solution out of the psyco cycle I remember referring to age 32 as the year that things were never the same as they were in my 20's.

    Mid 30's I had asked my ob/gyn if I could go back on the Ortho Novum 777. I was told that I was too old. This was early 2000's, 2003 or 2004. I was given a different birth control pill that he recommended and I tried that for a while but it wasn't making things better and I don't remember the exact details. I tried bio identical hormones... That wasn't really helpful either, it was more work and a long process that I stuck with for at least a year trying to get the formula right. I finally threw the towel in on that.

    Then a different ob/gyn suggested I try progesterone only. He prescribed a pink round ball of a pill. I was to take it the last 10 days of the month. I tried that for 3 or 4 months, it wasn't making things better... in fact I think it made it worse. Then I went cold turkey again for the better part of a year. At age 37, after not finding a doctor that was helping the situation I decided to find a doctor in AZ. I live full time in CA but had a vacation home in AZ so I thought I'd try that for a change.

    I did find a doctor and she prescribed yaz 24 day. She said it should help me as it has helped many other women. I took the yaz for a little better than a year and psychologically I thought I had a winner! This doctor sounded like she knew my problems and that this was the solution. Alas it was not. I remember feeling the most depressed is ever felt. I didn't think it had anything to do with the yaz, I figured it was just life. When I returned to that doctor after a year I explained my situation. She then recommended that I get an ablation!?! I was never a heavy bleeder and it makes no sense to have that done, but she sold me on the idea that it would help my problem. I realize now she was doing exactly that, selling. I'm sure it was a nice payment from the insurance company.

    None of my issues were solved. I had stopped taking the yaz or any birth control at that point. My period were non existent after boiling my uterus in boiling water, which is what the ablation is. And to this day my period is hardly worth talking about or being prepared for. It's spotting for a couple 3 days at best. With regard to my symptoms, the pms, pmdd, extreme irritability, depression all that stayed the same. I tried Seasonal for about 2 months and that was not good, it seemed to 'amp' the 'hot' - not physically hot but an irritable term I use to describe the upped level my nerves set at.

    I did exercise pretty regularly during all if this. The times I wasn't exercising were over the top as far as pmdd symptoms so that motivates you to get your rear to the gym. On the Yaz 24 day I knew something wasn't right. At day 14 I'd feel the symptoms if ovulation, not imagined but real. I was slightly irritable and had cramps for 2 to 3 days. At day 17, a Wednesday the irritability would ramp up and the depression would start to be present for the next 2 weeks.

    The following Wednesday was day 24, that was the last day of taking the pill. I did get a bit of relief after stopping the pill and 4 days later I resumed taking the next months pack on Sunday. The thing is I wouldn't get my period until Tuesday after I started the new pack? I know that my period should have happened between day 24 and 28 but it never did. It always started on day 31 or 32 and lasted 2 to 3 days. Then the whole cycle begins again with day 14.

    On Yaz 24

    Day 1 Sunday
    Day 3 or 4 Tuesday and my period would start.
    Day 5 or 6 my period ended
    Day 14 - Day 17 ovulation type cramping
    Day 17 irritability started ramping up into PMS, PMDD & Depression
    Symptoms were worse without exercise by at least 40%
    Day 24 Wednesday, last day of Yaz pack for the month
    Day 25 slight mood improvement
    Day 30-31 (same as Day 3/4above) period would start

    The ob/gyn expertise wasn't working, male or female. I went to my regular general practitioner for a check up and had done much research on the type of hormones in the Yaz, Yasmin and many others. I was convinced that I need to move over to Yasmin 21 day. It had a but more estrogen and it was only 21 instead of 24 days so worth a try.

    She asked me when the last time I felt 'normal' with regard to the hormones. I told her that as far as I can recall it was when I was in my 20's when I was taking the Ortho Novum 777. She said why don't we have you start taking that again! I was like, what? I explained I was told I could not take that because of my age and I thought some doctor had told me it had been discontinued years ago anyway. She said no, I can prescribe it to you, it's still available. I was a little excited about that. Maybe... just maybe that would be a solution for relief. My blood pressure is 100/70 always has been low, I don't smoke and I'm 5' 8", 150 pounds. She saw no reason for me not to try it again. We agreed that I would and if it didn't go well we'd try the Yasmin.

    I've been in the Ortho Novum, my package and brand saying Alyacen 7/7/7 for 3 weeks now. Today is Sunday and I stop taking active pills for 7 days now. At day 7 or so I noticed how much easier it was becoming to get out of bed in the morning. I began noticing I had an interest in getting something done. I didn't have a big heavy cloud urging me to just stay in bed. I started feeling alive again.

    The jury is still out and I have ordered a second months supply but I am deeply encouraged. During week 3 I have been crampier than on the yaz but in a very normal feeling way. Like my body is preparing for menstruation. I'm anticipating bleeding heavier than I'm used to, but in a good way. The cramping has been something I definitely notice much much more so but it's manageable. What I also notice is lack...... huge overwhelming lack of that horrible irritability. I'm more sensitive than weeks one and two but it's nothing by comparison. I've been more level headed, more 'normal'. Time will tell if this is my cure for the next 6 or so years but I'm extremely encouraged right now. I literally feel the best I have in years and there is some pretty crapy stressful things going on in my life. But I can handle them-

    Side note, I am a Type A personality. I am under a lot of stress running my own business often. I am a mother of 3 and a very capable woman. Watch out world if I'm back like my 20's nothing will stop me. I'm positive, excited and thankful for this moment.

    It stinks if this is this truly is the solution to my problem, as years of my life and those around me have been effected. But it does no good to look back I'm looking forward with great anticipation!

    Good Luck, I hope this monologue can help someone else just like me and I'll be saving a copy for future female generations of mine.

    God Bless
  • Long-term use of risperidone and antidepressants
    I have been using Risperdal and antidepressants for 14 years for bipolar disorder. Last month I was diagnosed with adrenal insufficiency and progesterone deficiency. My cholesterol suddenly became high, I was tired all the time and more symptoms relating to my eventual diagnosis of adrenal insufficiency and progesterone deficiency. I must also say that at the same time of starting treatment I stopped using birth control pills. I feel there needs to be caution taken in all of these drugs. They seem to have a severe effect on hormone balance in the body.
  • Lyrica varied widely
    I was prescribed Lyrica for treatment of chronic pain. It was ineffective, but it knocked out the symptoms of interstitial. However, it also caused rapid weight gain (I went from 110 to 130 lbs. in just a few weeks) and my ankles started to swell. The pain doctor advised me to discontinue the drug, but the urologist suggested lowering the dose. I did, and the swelling went down. I weighed myself daily and watched what I ate, and my weight returned to normal within a month. Subsequently, I continued taking the lower dose and had no further problems. Then I developed severe spinal stenosis, and my dosage of Lyrica was increased to six 75 capsules daily, in addition to 480 mg of morphine sulphate. I tolerated the Lyrica well. After surgery, however, my ankles began to swell again, and although I didn't have a problem with weight gain, I developed a bright red rash from ankles to knees. I dropped the dosage of Lyrica to 50 mg twice daily, and had no further side effects. The rash simply disappeared, with no damage to the skin. Following the surgery, I was able to titrate off morphine completely. I continue to take Lyrica twice daily. It doesn't seem to affect pain (I still ache a bit, as I have degenerative changes in all joints) but it does dampen peripheral neuropathy, which I experience both in my toes and balls of my feet. It also dampens the neuropathy in my forehead, where I had four surgeries to remove a malignant melanoma. I have had no side effects other than those mentioned, and find it interesting the I could tolerate a high dosage of Lyrica prior to surgery, but after surgery could not, and that adverse side effects varied not only with the dosage but with my own physical condition. I don't find it to be highly effective in treating neuropathy, but it does still the tingling enough to let me sleep and take my mind off the condition.

More reviews for: Progesterone, Weight gain

Comments from related studies:

  • From this study (5 months ago):

  • I started losing my hair more when I started taking the tramadol for pain. I have lost quite a bit of hair since then and started balding on the top of my head. I don't know if it is hormonal or from all the medication I am on because I know that can cause hair loss also. My hair is also limp and lifeless and I have gained about 15 pounds since being on the tramadol. It is the only medication that helps with my pain and chronic anxiety caused by the Cymbalta so I don't know what else to do.

    Reply

    axeman225 on Sep, 17, 2014:

    Hi! I am a 26yr old male. I saw this and seems like we are taking the same meds and I wanted to compare. I have been on tramadol for almost 3 years for herniated discs from playing football. I recently have noticed and heard that long term use affects testosterone levels, so I got bloodwork done...turns out I am below range on all levels...which sucks because I am fit (or was) and pretty big. So my doc prescribed testim 1% 50mg/day (as of yesterday) and I wanted to see how it affected you along with takign the tramadol. I dont have hair issues, but I have had weight gain and general feminization due to loss of testosterone....so gross and sad for me. Idk if you are male or female...but I would love to hear what the combo has done for you. If anyone else can chime in it would be great. (fyi..tramadol is a low dose opiate agonist for pain; testim is testosterone gel)

    Reply

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