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Review: could Promethazine cause Serotonin syndrome?





Summary: Serotonin syndrome is reported only by a few people who take Promethazine.

We study 609 people who have side effects while taking Promethazine from FDA and social media. Among them, 4 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

You are not alone: join a mobile support group for people who take Promethazine and have Serotonin syndrome >>>

Promethazine

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from Promethazine 1,213 users)

Serotonin syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, bipolar disorder.(latest reports from Serotonin syndrome 6,516 patients)

On Dec, 1, 2014: 609 people reported to have side effects when taking Promethazine. Among them, 4 people (0.66%) have Serotonin Syndrome.

Trend of Serotonin syndrome in Promethazine reports

Time on Promethazine when people have Serotonin syndrome * :

n/a

Gender of people who have Serotonin syndrome when taking Promethazine * :

FemaleMale
Serotonin syndrome100.00%0.00%

Age of people who have Serotonin syndrome when taking Promethazine * :

0-12-910-1920-2930-3940-4950-5960+
Serotonin syndrome0.00%0.00%0.00%0.00%0.00%100.00%0.00%0.00%

Severity of Serotonin syndrome when taking Promethazine ** :

n/a

How people recovered from Serotonin syndrome ** :

n/a

Top conditions involved for these people * :

  1. Fibromyalgia (4 people, 100.00%)

Top co-used drugs for these people * :

  1. Tramadol hydrochloride (4 people, 100.00%)
  2. Zestril (4 people, 100.00%)
  3. Savella (4 people, 100.00%)
  4. Lasix (4 people, 100.00%)
  5. Aspirin (3 people, 75.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Serotonin Syndrome while taking Promethazine?

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- support group for people who have Serotonin Syndrome

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    Fibromyalgia dx after pregnancy of only child at 42/other dx followed and seem to be in conjunction. heart issues did not appear until after the use of fibro meds- cymbalta, lyrica, neurontin, and more. had 1 seizure believed to be related to seretonin syndrome/years and years of mistreatment by doctors. unable to recall how many docs and meds through the years. one other very significant issue- after tooth extraction had puncture to left maxillary sinus-after YEARS of neglect by docs, found max. & ethmoid sinus completely opaque on CAT scan. Had surgery. Now, years later, have mucous plug that sporadically comes out upon sneezing. Fairly recent CAT scan shows sinuses again completely opaque. Certain needs further attention, but basically afraid to go through surgery again. Also- may have had heart attack. ER visit said no, but shortly after, had abnormal ekg. Again, neglect from docs. Am now active advocate for fm/chronic pain patients. Disgusted by the whole lack of interest of medical community. Looking for answers through my own research to try to find a way to improve quality of life...
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  • Husband died from depakene
    My husband took Depakene and Mysoline (Phenobarital) for 28 years. No hospital or physician checked his ammonia levels during these years. Ammonia levels needed to be checked every 6 months when taking Valproic Acid.



    As the result of no ammonia levels taken, he suffered from moderate severe atrophy of the brain, metabolic system was destroyed, regular system destroyed, 25 diagnoses due to the side effects of Depakene and died one year ago of mitochondrial encephalopathy.
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