Promethazine and Serotonin syndrome - from FDA reports
Serotonin syndrome is found among people who take Promethazine, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Metformin, and have Pain. This review analyzes which people have Serotonin syndrome with Promethazine. It is created by eHealthMe based on reports of 9,009 people who have side effects when taking Promethazine from FDA , and is updated regularly.
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On Sep, 26, 2017
9,009 people reported to have side effects when taking Promethazine.
Among them, 49 people (0.54%) have Serotonin syndrome
Number of reports submitted per year:
Time on Promethazine when people have Serotonin syndrome *:
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Serotonin syndrome when taking Promethazine *:
- female: 93.48 %
- male: 6.52 %
Age of people who have Serotonin syndrome when taking Promethazine *:
- 0-1: 0.0 %
- 2-9: 6.98 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 4.65 %
- 40-49: 34.88 %
- 50-59: 39.53 %
- 60+: 13.95 %
Top conditions involved for these people *:
- Stress And Anxiety (12 people, 24.49%)
- Pain (12 people, 24.49%)
- Depression (10 people, 20.41%)
- Schizophrenia (7 people, 14.29%)
- Procedural Pain (7 people, 14.29%)
Top co-used drugs for these people *:
- Metformin (16 people, 32.65%)
- Ondansetron (15 people, 30.61%)
- Morphine (12 people, 24.49%)
- Clozapine (11 people, 22.45%)
- Benadryl (10 people, 20.41%)
Top other side effects for these people *:
- Agitation (11 people, 22.45%)
- Pain (8 people, 16.33%)
- Clonus (8 people, 16.33%)
- Pollakiuria (6 people, 12.24%)
- Fall (6 people, 12.24%)
* Approximation only. Some reports may have incomplete information.
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Expand the study to include all drugs with the same ingredientsSerotonin syndrome and drugs with ingredients of promethazine hydrochloride.
Expand the study to include reports from both FDA and eHealthMeSerotonin syndrome and Promethazine from FDA and eHealthMe reports
Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (latest outcomes from Promethazine 9,862 users)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with depression, pain, stress and anxiety, major depression, insomnia (latest reports from 10,388 Serotonin syndrome patients).
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Questions to the study
Hello,I'm Silvia Ramakers and i live in the netherlands. I have Gorlin probably since i was about 15 (diagnosed at older age,i'm almost 50 now btw). Had many BCC's through the years. But why i'm writing (and i hope anybody can help because i'm desperate) is that since a while i have more and ...
I think I have serotonin syndrome which brought on a multiple sclerosis relapse only the doctor doesn't think so. I was diagnosed with MS Jan 2008 and had a relapse a month or two later. I haven't had one since until now. I eat healthy and exercise (I cycle and swim, nothing to strenuous)and ...
User reviews to the study
I have a cousin we just lost. She was 58 and she died in her sleep. She has been on multiple medications most of her adult life. She did take seroquel and migraine medicine. Has anybody in the group lost someone to seroquel syndrome?
Hi. Was on Amitriptyline for years and gain lots of weight. As replacement doctor prescribed Promethazine as medicine without weight gain side effect. Any body knows is it for better or for worse? Thank you for sharing your opinion With kind regards Casandra
Someone very close to me is in the final stages of stage four prostate cancer and was recently switched from Zofran to the topical form of promethazine. Since I am the primary caregiver, I have noticed that each time he falls asleep since starting the promethazine his hands are constantly moving ...
Hi I know my answer is late Hi I know my answer is late for yout post, and I hope you are doing better today. I suffered severe serotonin syndrome in Jan and Feb 2016. Hospitalized and in ICU on ventilator for 3 days. I was taking cymbalta and psychiatrist ordered buspar. I took the buspar x2 ...