Review: could Propranolol hydrochloride cause Hypothyroidism?
Summary: Hypothyroidism is found among people who take Propranolol hydrochloride, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Fosamax, and have Osteoporosis.
We study 2,516 people who have side effects while taking Propranolol hydrochloride from FDA and social media. Among them, 13 have Hypothyroidism. Find out below who they are, when they have Hypothyroidism and more.
You are not alone: join a mobile support group for people who take Propranolol hydrochloride and have Hypothyroidism >>>
Propranolol hydrochloride has active ingredients of propranolol hydrochloride. It is often used in stress and anxiety. (latest outcomes from 3,354 Propranolol hydrochloride users)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) has been reported by people with osteoporosis, high blood pressure, osteopenia, depression, multiple sclerosis. (latest reports from 49,613 Hypothyroidism patients)
On Feb, 9, 2015: 2,508 people reported to have side effects when taking Propranolol hydrochloride. Among them, 13 people (0.52%) have Hypothyroidism.
Time on Propranolol hydrochloride when people have Hypothyroidism * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
Gender of people who have Hypothyroidism when taking Propranolol hydrochloride * :
Age of people who have Hypothyroidism when taking Propranolol hydrochloride * :
Severity of Hypothyroidism when taking Propranolol hydrochloride ** :
|least||moderate||severe||most severe |
How people recovered from Hypothyroidism ** :
|while on the drug||after off the drug||not yet |
Top conditions involved for these people * :
- Osteoporosis (4 people, 30.77%)
- Lipids (3 people, 23.08%)
- Anaemia (3 people, 23.08%)
- Bone density decreased (3 people, 23.08%)
- Hypertension (3 people, 23.08%)
Top co-used drugs for these people * :
- Fosamax (4 people, 30.77%)
- Aspirin (4 people, 30.77%)
- Zocor (4 people, 30.77%)
- Allopurinol (3 people, 23.08%)
- Dyrenium (3 people, 23.08%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.
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In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started.
My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have now been on 60mg of Cymbalta for about 4 weeks and completely titrated off the Mirtazapine.
I have noted that since switching to Cymbalta that I no longer have the insatiable appetite, nor have I had any further sleep paralysis episodes (though I have had a brain MRI to rule out any physiological issues - yet to receive results).
I have noticed that I have had mild to moderate rolling nausea with the Cymbalta and that I now have food aversions. Food does not interest me as much anymore and I find that certain foods (mostly processed snacks) are no longer palatable. I also find that I become full after much smaller meal portions.
I have found that I can no longer drink wine or spirits because they now taste awful however I can still tolerate certain brands of beer. I also no longer enjoy drinking cola.
I am also on the Implanon Implant. I have had this implant inserted for about 12 months and my cycles have been rather regular. Since starting the Cymbalta I have had some breakthrough bleeding yet my periods have not been as painful, though they have been heavier and longer.
My Psychiatrist will commence titrating me off the Seroquel in about two weeks and onto Topamax as it is his belief it will be less sedating than the Seroquel and that it will hopefully help as a mood stabiliser, treat my migraines and allow me to come off the Propranolol. he also hopes that I am able to loose some of the weight gained since the sleep paralysis episodes started.
As a side note regarding the Propranolol, I have naturally low blood pressure and I find while Propranalol is generally an effective migraine prophylactic, (I do get some breakthrough migraines) it does make my blood pressure even lower which leads to dizziness and faintness when I stand up too quickly from a recumbent position.
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One year ago, after being on Lyrica for 5 years, I developed extreme tooth sensitivity. It came on very quickly to one tooth, then quickly spread to all of my top front 6 teeth and now the rest of my teeth are sensitive too. When I say sensitive, I mean that I can't even bite a banana using my front teeth!!! I ended up having root canals on my top front 4 teeth and then had to have two of them pulled because even after the root canals, they were extremely sensitive to any sort of touch at all!!! I now have implants for those two teeth and yet the sensitivity continues in the rest of my teeth. The dentist, endodontist, periodontist and family physician can find nothing 'physically' wrong. My gums are healthy. I feel that it is somehow nerve related and that there has been some damage done. I can not even form words properly because my tongue hits the back of my front teeth as I talk (which is normal), but even THAT causes me pain. I have to constantly use Tylenol and Advil (although they really don't give me any relief.) I have gone through no less than 20 tubes of Orajel and Ambesol in the past year. It is pretty much the only thing that gives me any sort of relief. It has completely affected my quality of life, (as if the reason I needed the Lyrica in the first place didn't already do that enough!!) I am confident that it is the Lyrica as I can find no other literature on the Propranolol causing any side effects such as this. I am a very fit, active lady. I happen to have P.O.T.S which is why I am on the Beta Blocker and Lyrica in the first place. I sure hope that if I stop taking the Lyrica, the sensitivity will decrease. At this rate, I'm going to lose all of my teeth! Incidentally, two of my otherwise healthy teeth now feel wiggly as well! Up until recently, I had only typical, age related dental issues. My dentist is perplexed as to what is going on with me. This is so frustrating!
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Comments from related studies:
From this study (4 weeks ago):
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