Review: could Provigil cause Somnolence?


Somnolence is found among people who take Provigil, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Cymbalta, and have Pain . We study 10,474 people who have side effects while taking Provigil from FDA and social media. Among them, 464 have Somnolence. Find out below who they are, when they have Somnolence and more.

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Provigil has active ingredients of modafinil. It is often used in fatigue. (latest outcomes from Provigil 11,084 users)


Somnolence (a state of near-sleep, a strong desire for sleep) has been reported by people with weight decreased, breathing difficulty, feeling abnormal, diarrhea, heart palpitations (latest reports from 77,379 Somnolence patients).

On Aug, 24, 2016

10,474 people reported to have side effects when taking Provigil.
Among them, 464 people (4.43%) have Somnolence

Number of reports submitted per year:

Could Provigil cause Somnolence?

Time on Provigil when people have Somnolence *:

  • < 1 month: 35.0 %
  • 1 - 6 months: 18.33 %
  • 6 - 12 months: 8.33 %
  • 1 - 2 years: 18.33 %
  • 2 - 5 years: 11.67 %
  • 5 - 10 years: 8.33 %
  • 10+ years: 0.0 %

Gender of people who have Somnolence when taking Provigil *:

  • female: 68.26 %
  • male: 31.74 %

Age of people who have Somnolence when taking Provigil *:

  • 0-1: 0.0 %
  • 2-9: 1.36 %
  • 10-19: 2.44 %
  • 20-29: 3.52 %
  • 30-39: 8.94 %
  • 40-49: 26.56 %
  • 50-59: 32.52 %
  • 60+: 24.39 %

Severity if Somnolence when taking Provigil **:

  • least: 8.33 %
  • moderate: 50.0 %
  • severe: 33.33 %
  • most severe: 8.33 %

Top conditions involved for these people *:

  • Pain (65 people)
  • Depression (64 people)
  • Multiple Sclerosis (62 people)
  • Insomnia (37 people)
  • Gastrooesophageal Reflux Disease (36 people)

Top co-used drugs for these people *:

  • Cymbalta (75 people)
  • Nexium (65 people)
  • Neurontin (60 people)
  • Klonopin (57 people)
  • Lexapro (54 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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