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Review: could Prozac cause Irritability?

Summary: Irritability could be caused by Prozac, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take Xanax, and have Depression.

We study 38,735 people who have side effects while taking Prozac from FDA and social media. Among them, 505 have Irritability. Find out below who they are, when they have Irritability and more.

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Prozac

Prozac (latest outcomes from 42,009 users) has active ingredients of fluoxetine hydrochloride. It is often used in depression.

Irritability

Irritability (latest reports from 145,499 patients) has been reported by people with depression, quit smoking, pain, stress and anxiety, attention deficit hyperactivity disorder.

On Apr, 10, 2014: 38,676 people reported to have side effects when taking Prozac. Among them, 506 people (1.31%) have Irritability. They amount to 0.35% of all the 145,240 people who have Irritability on eHealthMe.

Trend of Irritability in Prozac reports

Time on Prozac when people have Irritability * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Irritability24.49%20.41%6.12%24.49%12.24%2.04%10.20%

Age of people who have Irritability when taking Prozac * :

0-12-910-1920-2930-3940-4950-5960+
Irritability1.13%1.81%8.82%9.73%16.52%33.26%19.46%9.28%

Severity of Irritability when taking Prozac ** :

leastmoderateseveremost severe
Irritability0.00%60.00%40.00%0.00%

How people recovered from Irritability ** :

while on the drugafter off the drugnot yet
Irritability0.00%33.33%66.67%

Top conditions involved for these people * :

  1. Depression (147 people, 29.05%)
  2. Pain (65 people, 12.85%)
  3. Anxiety (54 people, 10.67%)
  4. Bipolar disorder (35 people, 6.92%)
  5. Smoking cessation therapy (33 people, 6.52%)

Top co-used drugs for these people * :

  1. Xanax (85 people, 16.80%)
  2. Neurontin (69 people, 13.64%)
  3. Seroquel (61 people, 12.06%)
  4. Oxycontin (60 people, 11.86%)
  5. Ambien (59 people, 11.66%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Prozac, Irritability

You can also:

On eHealthMe, Prozac (fluoxetine hydrochloride) is often used for depression. Find out below the conditions Prozac is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Prozac used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 years ago):

  • I have just had my topamax increased and as it did when I first began, I have this overall feeling of sadness and malaise. Im wondering if its the combination of the medication or just the topamax. It does eventually dissipate, but the feeling sucks! Its as though im never going to be cheerful again. And when I become angry, I become enraged and even irrational! Not me at all.

    Reply

    ed on Oct, 12, 2012:

    I am a 43 year old male. I had a shoulder in January and went to a pain management clinic in June and been taking Topamax since then. I understand how you feel especially when they upped my grams from 50 to 100 a day. My feelings got darker. I am currently trying to get off the medication. I hope all goes well with you.

    Reply

  • From this study (2 years ago):

  • Tim J on Jul, 10, 2011:

    I took this drug and it killed 40 percent of my achilles tendon.

    Reply

    George P on May, 7, 2012:

    I developed torticollis soon after starting abilify. At the same time, I developed pain in my left side. An MRI revealed 4 ruptured disks in my spine, a known cause of torticollis.

    Conclusion: I have no idea (neither, it seems, do the doctors). But I found abilify very effective for its purpose.

    Reply

  • From this study (5 years ago):

  • Fluoxetine has always worked well for my depression. Since starting on Niacin three weeks ago, I have been more irritable and sad.

    Reply

Can you answer these questions (what is this?):

More questions for: Prozac, Irritability

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