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Review: could Rebif cause Muscle spasticity?

Summary: Muscle spasticity is found among people who take Rebif, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take medication Baclofen, and have Multiple sclerosis.

We study 32,035 people who have side effects while taking Rebif from FDA and social media. Among them, 153 have Muscle spasticity. Find out below who they are, when they have Muscle spasticity and more.

You are not alone: join a mobile support group for people who take Rebif and have Muscle spasticity >>>


Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. (latest outcomes from Rebif 32,157 users)

Muscle spasticity

Muscle spasticity (tight or stiff muscles and an inability to control those muscles) has been reported by people with multiple sclerosis, depression, pain, relapsing-remitting multiple sclerosis, stress and anxiety.(latest reports from Muscle spasticity 14,816 patients)

On Nov, 28, 2014: 32,035 people reported to have side effects when taking Rebif. Among them, 153 people (0.48%) have Muscle Spasticity.

Trend of Muscle spasticity in Rebif reports

Time on Rebif when people have Muscle spasticity * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Muscle spasticity8.70%15.22%10.87%17.39%36.96%6.52%4.35%

Gender of people who have Muscle spasticity when taking Rebif * :

Muscle spasticity76.57%23.43%

Age of people who have Muscle spasticity when taking Rebif * :

Muscle spasticity0.00%0.00%0.66%8.55%24.34%25.00%25.00%16.45%

Severity of Muscle spasticity when taking Rebif ** :


How people recovered from Muscle spasticity ** :


Top conditions involved for these people * :

  1. Multiple sclerosis (125 people, 81.70%)
  2. Relapsing-remitting multiple sclerosis (15 people, 9.80%)
  3. Depression (8 people, 5.23%)
  4. Pain (6 people, 3.92%)
  5. Secondary progressive multiple sclerosis (5 people, 3.27%)

Top co-used drugs for these people * :

  1. Baclofen (32 people, 20.92%)
  2. Ibuprofen (12 people, 7.84%)
  3. Amantadine hcl (10 people, 6.54%)
  4. Neurontin (9 people, 5.88%)
  5. Provigil (8 people, 5.23%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Muscle Spasticity while taking Rebif?

You are not alone! Join a mobile support group:
- support group for people who take Rebif and have Muscle Spasticity
- support group for people who take Rebif
- support group for people who have Muscle Spasticity

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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