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Review: could Rebif cause Muscle spasticity?

Summary: Muscle spasticity is found among people who take Rebif, especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take medication Baclofen, and have Multiple sclerosis.

We study 32,036 people who have side effects while taking Rebif from FDA and social media. Among them, 153 have Muscle spasticity. Find out below who they are, when they have Muscle spasticity and more.

You are not alone: join a mobile support group for people who take Rebif and have Muscle spasticity >>>

 

 

 

 

Rebif

Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. (latest outcomes from 32,159 Rebif users)

Muscle spasticity

Muscle spasticity (tight or stiff muscles and an inability to control those muscles) has been reported by people with multiple sclerosis, depression, pain, relapsing-remitting multiple sclerosis, stress and anxiety. (latest reports from 14,904 Muscle spasticity patients)

On Feb, 12, 2015: 32,036 people reported to have side effects when taking Rebif. Among them, 153 people (0.48%) have Muscle Spasticity.

Trend of Muscle spasticity in Rebif reports

Time on Rebif when people have Muscle spasticity * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Muscle spasticity8.70%15.22%10.87%17.39%36.96%6.52%4.35%

Gender of people who have Muscle spasticity when taking Rebif * :

FemaleMale
Muscle spasticity76.57%23.43%

Age of people who have Muscle spasticity when taking Rebif * :

0-12-910-1920-2930-3940-4950-5960+
Muscle spasticity0.00%0.00%0.66%8.55%24.34%25.00%25.00%16.45%

Severity of Muscle spasticity when taking Rebif ** :

n/a

How people recovered from Muscle spasticity ** :

n/a

Top conditions involved for these people * :

  1. Multiple sclerosis (125 people, 81.70%)
  2. Relapsing-remitting multiple sclerosis (15 people, 9.80%)
  3. Depression (8 people, 5.23%)
  4. Pain (6 people, 3.92%)
  5. Secondary progressive multiple sclerosis (5 people, 3.27%)

Top co-used drugs for these people * :

  1. Baclofen (32 people, 20.92%)
  2. Ibuprofen (12 people, 7.84%)
  3. Amantadine hcl (10 people, 6.54%)
  4. Neurontin (9 people, 5.88%)
  5. Provigil (8 people, 5.23%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Muscle Spasticity while taking Rebif?

You are not alone! Join a mobile support group:
- support group for people who take Rebif and have Muscle Spasticity
- support group for people who take Rebif
- support group for people who have Muscle Spasticity

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Comments from related studies:

  • From this study (7 months ago):

  • My son began having autistic tantrums at school & would pound his head on the floor; neurologist prescribed Celexa to stop self-injurious behavior. After 2 years,doctor changed prescription to Lexapro. Experienced pain in feet/lower legs upon standing/walking more than 1 hour. Age 11 (2006), nerve disfunction began (said his feet felt "sparkly"). I noticed left leg bowing out at knee when he walked down stairs. Began severe muscle spasms when laid down to go to sleep. The spasms/nerve pain became severe & increased difficulty falling/staying asleep. Spasms continued through 1st 1-2 hours of sleep; spasms drew his leg/legs up like a frog. Slept through spasms; they occurred every night & followed a full-body "jerk". Spasms always occurred on the left, & right leg would draw up into a frogleg position. Doctor added Seroquel for severe insomnia. Podiatrist diagnosed shortened achiles tendons in feet/ankles. 6 months after the spasms began, left foot began to change & severe episodes of memory loss occurred(he did not where he was, who he was or who his teachers, classmates, or I were). Would scream & hit his head with his fists. Doctor suspected ALD; tests were negative. W/in 4 months (age 12), left foot deformed into clubfoot/calf smaller. Diagnosed w/spasticity, dystonia, cerebral palsy. Since achiles tendon/club foot developed, can't stand/walk more than 20-30 minutes without foot/leg pain. Doctors suspect neuromuscular disorder but have not diagnosed specific type. 2008-2009, had botox injections in calves but treatment stopped working. Had 2 foot surgeries in 2009 to reposition left foot & release achiles tendon. Left foot much shorter, wider & thicker than right. Developed dystonia/spasticity in forearms/hands 2008. Taking Tizanidine and Mirapex for help control/lesson the spasming & nerve disfunction since 2008. Weaned off Seroquel & Lexapro (2011/2012), because Seroquel made drowsy/caused Acanthosis nigricans; Lexapro made confused.

    Reply

    jennifer on Jul, 27, 2014:

    Female 39, have had 2.5 years enlarged groin muscle serve pain in trochanter area, priformus, more recently now also have cervical dystonia, 9 Weeks now. One of my scans of hips said nail patella syndrom can you tell me more about that, what or means for you, or where to get info.

    Thanks

    Reply

    Christi on Oct, 11, 2012:

    How do his thumb nails look? Are they absent or split, or have a triangular lunulae? If yes to any of these questions, please research a genetic disease called Nail Patella Syndrome. Myself and 3 of my 4 children have it. Good luck!

    Reply

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