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Review: could Remicade cause Anaphylactic shock (Anaphylaxis)?





Summary: Anaphylactic shock is found among people who take Remicade, especially for people who are female, 10-19 old, have been taking the drug for < 1 month, also take medication Methotrexate, and have Crohn's disease.

We study 85,085 people who have side effects while taking Remicade from FDA and social media. Among them, 732 have Anaphylactic shock. Find out below who they are, when they have Anaphylactic shock and more.

You are not alone: join a mobile support group for people who take Remicade and have Anaphylactic shock >>>

Remicade

Remicade has active ingredients of infliximab. It is often used in crohn's disease. (latest outcomes from Remicade 85,488 users)

Anaphylactic shock

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance) has been reported by people with multiple sclerosis, asthma, high blood pressure, premedication, pain.(latest reports from Anaphylactic shock 28,821 patients)

On Dec, 1, 2014: 85,085 people reported to have side effects when taking Remicade. Among them, 732 people (0.86%) have Anaphylactic Shock.

Trend of Anaphylactic shock in Remicade reports

Time on Remicade when people have Anaphylactic shock * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anaphylactic shock63.72%12.56%6.05%9.77%6.98%0.93%0.00%

Gender of people who have Anaphylactic shock when taking Remicade * :

FemaleMale
Anaphylactic shock61.95%38.05%

Age of people who have Anaphylactic shock when taking Remicade * :

0-12-910-1920-2930-3940-4950-5960+
Anaphylactic shock0.00%8.00%22.49%13.94%16.94%9.98%14.89%13.78%

Severity of Anaphylactic shock when taking Remicade ** :

n/a

How people recovered from Anaphylactic shock ** :

n/a

Top conditions involved for these people * :

  1. Crohn's disease (545 people, 74.45%)
  2. Rheumatoid arthritis (284 people, 38.80%)
  3. Psoriasis (84 people, 11.48%)
  4. Colitis ulcerative (77 people, 10.52%)
  5. Psoriatic arthropathy (74 people, 10.11%)

Top co-used drugs for these people * :

  1. Methotrexate (284 people, 38.80%)
  2. Prednisolone (148 people, 20.22%)
  3. Prednisone (114 people, 15.57%)
  4. Pentasa (113 people, 15.44%)
  5. Folic acid (92 people, 12.57%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Anaphylactic Shock while taking Remicade?

You are not alone! Join a mobile support group:
- support group for people who take Remicade and have Anaphylactic Shock
- support group for people who take Remicade
- support group for people who have Anaphylactic Shock

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Seizure after an epipen injection (1 answer)
    I am allergic to EVERYTHING, so I usually pre-game with benadryl and wait out the uncomfortable side effects, but this time my tongue started swelling up and I was having trouble breathing so I went to an ER. About 5-7 minutes after they injected me in the thigh with an epipen, I was in mid sentence when I started having strange sensations and tremors all over my body. The injection spot, which is incredibly sore and feels like they hit my femur) suddenly became very warm and I could feel it spreading out quickly. I could hear people but I couldn't speak, everything clamped up, I couldn't breathe and I felt very confused and forgot what I was about to say to the nurse. The doctor caught the tail end of it and claimed I was having a panic attack! I heard both the nurses say that they thought it was a seizure. This happened to me once more a few yrs ago with an allergic reaction, but it was from the nurse pushing in the benadryl too quickly, which made my hands curl up like T-Rex and my eyes rolled back into my head. Is there such a thing as being allergic to epinephrine or has anyone ever experienced a seizure/stroke like reaction after being administered Epipen or Benadryl ?
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  • Is it safe to take pravastin while on remicade?
    I have just started on Remicade and this drug scares the heck out of me! However it is being used as a last resort as no other medications were bring my ulcerative colitis under control I am very concerned about drug interactions and can't seem to get any straight answers from my doctor or the pharmacist. My main concern right now is can I safely take Pravastian due to being on Remicade? My cholesterol is very high.
    Reply
  • Can thyroid problems bring on anaphylaxis often?
    70 yr old previously stong female: Suspicious of thyroid problems...family history. Fatigue, skin, hair changes, slightly swollen, tender tongue at all times. In the last 6 months I've developed food related anaphalaxis. Getting serious, 3 E.R. runs in last 3 months....packing 2 epipens at all times. Endocrinologist apt not until mid December. I can't seem to stay clear of anaphalaxis long enough to get to the Allergist's for those blood tests.

    Any one else gone this route?
    Reply
  • Remicade or ulcerative colitis causing joint pain?
    Im also on mesalamine, 6 mp and trazadone. Ive had joint pain in elbow before but i realised it was caused by taking cortenema. I stoped the med and pain went away. After my first infusion of remicade (2days) i started with the knee, ankle, elbows , wrists and hands pain. The more i do. The worst the pain gets. Dr seemed to think it was caused by the UC but the timming of when the pain started is too close to e remicade. Ive had 3 doses. Still in pain every day. UC symptoms are much less severe than before. So why would the UC cause my joint pain?
    Reply
  • I am experiencing myelodysplastic syndrome symptoms but it is said that it doesn't typically get diagnosed for people my age. although everything is spot on and i need to know whats wrong.
    I have been doing remicade treatments for about four years now. Lately I have gotten a UTI, an I get random bruises every single day, I also get super tired, my body aches, and I get fevers for hours on end without them breaking. I have no idea whats wrong because this has never happened before but someone told me that it looks like MDS and I looked into it and I have all the symptoms just am not in the age group for it. I was hoping someone would know if there is anything else I could look up. I am aware that remicade long term wise can cause leukemia and that is why this is such a huge concern. Please give me feedback thank you.
    Reply

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    Within the first week of usage, I began to have leg cramps, facial swelling, tightness of breath, chest pain, anxiety, and chronic headaches. Even with allergy medicines and aspirin, nothing seemed to help. At first, I felt it was though it was just simple allergies until I woke up one morning with my face so swollen that I could see my skin around my eyes without looking in a mirror. My throat began to swell to the point it was difficult to swallow. I immediately went to the ER to receive a shot and sleep all day with Benadryl. The following day, I have redness in the skin and hoarseness. The doctor told me too never touch Rogaine again or I would end up in the hospital (or worse).
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