Review: could Remicade cause Hepatosplenic T-cell Lymphoma?


Summary

Hepatosplenic t-cell lymphoma is found among people who take Remicade, especially for people who are male, 20-29 old , have been taking the drug for 2 - 5 years, also take medication Mercaptopurine, and have Crohn's disease . We study 97,679 people who have side effects while taking Remicade from FDA and social media. Among them, 283 have Hepatosplenic t-cell lymphoma. Find out below who they are, when they have Hepatosplenic t-cell lymphoma and more.

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Remicade

Remicade has active ingredients of infliximab. It is often used in rheumatoid arthritis. (latest outcomes from Remicade 96,123 users)

Hepatosplenic T-cell Lymphoma

Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow) (latest reports from 378 Hepatosplenic t-cell lymphoma patients).

On Aug, 20, 2016

97,679 people reported to have side effects when taking Remicade.
Among them, 283 people (0.29%) have Hepatosplenic T-cell Lymphoma


Number of reports submitted per year:

Could Remicade cause Hepatosplenic t-cell lymphoma?

Time on Remicade when people have Hepatosplenic T-cell Lymphoma *:

  • < 1 month: 18.46 %
  • 1 - 6 months: 27.69 %
  • 6 - 12 months: 4.62 %
  • 1 - 2 years: 1.54 %
  • 2 - 5 years: 44.62 %
  • 5 - 10 years: 1.54 %
  • 10+ years: 1.54 %

Gender of people who have Hepatosplenic T-cell Lymphoma when taking Remicade *:

  • female: 12.31 %
  • male: 87.69 %

Age of people who have Hepatosplenic T-cell Lymphoma when taking Remicade *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 25.23 %
  • 20-29: 34.4 %
  • 30-39: 26.15 %
  • 40-49: 0.92 %
  • 50-59: 8.72 %
  • 60+: 4.59 %

Top conditions involved for these people *:

  • Crohn's Disease (229 people)
  • Colitis Ulcerative (45 people)
  • Inflammatory Bowel Disease (14 people)
  • Gastrooesophageal Reflux Disease (10 people)
  • Diarrhoea (10 people)

Top co-used drugs for these people *:

  • Mercaptopurine (105 people)
  • Azathioprine (93 people)
  • Imuran (59 people)
  • Asacol (54 people)
  • Humira (44 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Hepatosplenic t-cell lymphoma when taking Remicade?

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