Review: could Ritalin cause Irritability?


Irritability is found among people who take Ritalin, especially for people who are male, 10-19 old , have been taking the drug for 1 - 6 months, also take medication Prozac, and have Attention deficit/hyperactivity disorder . We study 9,660 people who have side effects while taking Ritalin from FDA and social media. Among them, 143 have Irritability. Find out below who they are, when they have Irritability and more.

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Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. (latest outcomes from Ritalin 12,382 users)


Irritability has been reported by people with fever, rashes, drug ineffective, weight increased, insomnia (latest reports from 27,708 Irritability patients).

On Aug, 25, 2016

9,660 people reported to have side effects when taking Ritalin.
Among them, 143 people (1.48%) have Irritability

Number of reports submitted per year:

Could Ritalin cause Irritability?

Time on Ritalin when people have Irritability *:

  • < 1 month: 16.67 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 25.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 8.33 %
  • 5 - 10 years: 16.67 %
  • 10+ years: 0.0 %

Gender of people who have Irritability when taking Ritalin *:

  • female: 40.14 %
  • male: 59.86 %

Age of people who have Irritability when taking Ritalin *:

  • 0-1: 1.92 %
  • 2-9: 17.31 %
  • 10-19: 24.04 %
  • 20-29: 10.58 %
  • 30-39: 16.35 %
  • 40-49: 19.23 %
  • 50-59: 6.73 %
  • 60+: 3.85 %

Severity if Irritability when taking Ritalin **:

  • least: 50 %
  • moderate: 0.0 %
  • severe: 50 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Attention Deficit/hyperactivity Disorder (48 people)
  • Depression (20 people)
  • Osteoporosis (8 people)
  • Neoplasm Malignant (8 people)
  • Metastases To Bone (8 people)

Top co-used drugs for these people *:

  • Prozac (26 people)
  • Wellbutrin (18 people)
  • Paxil (15 people)
  • Strattera (14 people)
  • Neurontin (14 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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