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Review: could Rituxan cause Rigors?

Summary: Rigors could be caused by Rituxan, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Benadryl, and have Non-hodgkin's lymphoma.

We study 10,182 people who have side effects while taking Rituxan from FDA and social media. Among them, 455 have Rigors. Find out below who they are, when they have Rigors and more.

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Rituxan

Rituxan (latest outcomes from 10,289 users) has active ingredients of rituximab. It is often used in rheumatoid arthritis.

Rigors

Rigors (an episode of shaking or exaggerated shivering) (latest reports from 249,226 patients) has been reported by people with multiple sclerosis, rheumatoid arthritis, high blood pressure, osteoporosis, pain.

On Apr, 11, 2014: 10,178 people reported to have side effects when taking Rituxan. Among them, 455 people (4.47%) have Rigors. They amount to 0.18% of all the 248,557 people who have Rigors on eHealthMe.

Trend of Rigors in Rituxan reports

Time on Rituxan when people have Rigors * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Rigors81.63%16.33%2.04%0.00%0.00%0.00%0.00%

Gender of people who have Rigors when taking Rituxan * :

FemaleMale
Rigors42.32%57.68%

Age of people who have Rigors when taking Rituxan * :

0-12-910-1920-2930-3940-4950-5960+
Rigors0.00%0.46%0.00%2.53%1.84%13.82%18.66%62.67%

Severity of Rigors when taking Rituxan ** :

leastmoderateseveremost severe
Rigors0.00%0.00%100.00%0.00%

How people recovered from Rigors ** :

n/a

Top conditions involved for these people * :

  1. Non-hodgkin's lymphoma (77 people, 16.92%)
  2. Chronic lymphocytic leukaemia (49 people, 10.77%)
  3. Lymphoma (39 people, 8.57%)
  4. B-cell lymphoma (13 people, 2.86%)
  5. Rheumatoid arthritis (8 people, 1.76%)

Top co-used drugs for these people * :

  1. Benadryl (45 people, 9.89%)
  2. Tylenol (35 people, 7.69%)
  3. Allopurinol (34 people, 7.47%)
  4. Prednisone (34 people, 7.47%)
  5. Cyclophosphamide (32 people, 7.03%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Rituxan, Rigors

You can also:

On eHealthMe, Rituxan (rituximab) is often used for rheumatoid arthritis. Find out below the conditions Rituxan is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Rituxan used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 years ago):

  • 1st chemo rx 10/5 - 10/7 along with allopurinol - completed allopurinol 10/26 became symptomatic 10/31 hospitalized 11/3 - 11/6, 11/7 rash become more severe - complete skin exfoliation several layers at a time - still experiencing some skin turnover. 2nd chemo - treanda only 12/5 & 12/6 presents with 99.5 fever and chills, trembling (shivering) 2 220 mg alleve - symptoms subsided to some degree. scheduled for rituxan tomorrow - afraid of possible outcome - oh and no cancer cells noted after 1st chemo rx.

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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