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Review: could Saphris cause Hypertension (High blood pressure)?

Summary: Hypertension is found among people who take Saphris, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take medication Metopolol, and have Bipolar disorder.

We study 3,976 people who have side effects while taking Saphris from FDA and social media. Among them, 40 have Hypertension. Find out below who they are, when they have Hypertension and more.

You are not alone: join a support group for people who take Saphris and have Hypertension >>>



Saphris has active ingredients of asenapine maleate. It is often used in bipolar disorder. (latest outcomes from 4,057 Saphris users)


Hypertension (high blood pressure) has been reported by people with high blood pressure, osteoporosis, depression, multiple sclerosis, pain. (latest reports from 352,051 Hypertension patients)

On Mar, 13, 2015: 3,976 people reported to have side effects when taking Saphris. Among them, 40 people (1.01%) have Hypertension.

Trend of Hypertension in Saphris reports

Time on Saphris when people have Hypertension * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Hypertension when taking Saphris * :


Age of people who have Hypertension when taking Saphris * :


Severity of Hypertension when taking Saphris ** :


How people recovered from Hypertension ** :


Top conditions involved for these people * :

  1. Bipolar disorder (8 people, 20.00%)
  2. Hypertension (5 people, 12.50%)
  3. Dementia alzheimer's type (4 people, 10.00%)
  4. Schizophrenia (3 people, 7.50%)
  5. Psychotic disorder (3 people, 7.50%)

Top co-used drugs for these people * :

  1. Metopolol (4 people, 10.00%)
  2. Seroquel (4 people, 10.00%)
  3. Celexa (4 people, 10.00%)
  4. Hydrochlorothiazide (4 people, 10.00%)
  5. Crestor (4 people, 10.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of saphris and hypertension on

Do you have Hypertension while taking Saphris?




You are not alone! Join a mobile support group on :
- support group for people who take Saphris and have Hypertension
- support group for people who take Saphris
- support group for people who have Hypertension

Drugs in real world that are associated with:

Could your condition cause:

Recent related drug studies (Check your drugs):

Recent Saphris related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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