Review: could Seroquel cause Serotonin Syndrome?


Serotonin syndrome is found among people who take Seroquel, especially for people who are female, 50-59 old , have been taking the drug for < 1 month, also take medication Zoloft, and have Depression . We study 68,654 people who have side effects while taking Seroquel from FDA and social media. Among them, 181 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

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Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 77,696 users)

Serotonin Syndrome

Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time) has been reported by people with disease complication, insomnia, feeling jittery, vaginal discharge, bruxism (latest reports from 6,752 Serotonin syndrome patients).

On Aug, 17, 2016

68,654 people reported to have side effects when taking Seroquel.
Among them, 181 people (0.26%) have Serotonin Syndrome

Number of reports submitted per year:

Could Seroquel cause Serotonin syndrome?

Time on Seroquel when people have Serotonin Syndrome *:

  • < 1 month: 62.16 %
  • 1 - 6 months: 16.22 %
  • 6 - 12 months: 8.11 %
  • 1 - 2 years: 13.51 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Serotonin Syndrome when taking Seroquel *:

  • female: 64.63 %
  • male: 35.37 %

Age of people who have Serotonin Syndrome when taking Seroquel *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.6 %
  • 20-29: 15.11 %
  • 30-39: 17.99 %
  • 40-49: 22.3 %
  • 50-59: 23.02 %
  • 60+: 17.99 %

Severity if Serotonin Syndrome when taking Seroquel **:

  • least: 0.0 %
  • moderate: 100 %
  • severe: 0.0 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Depression (51 people)
  • Bipolar Disorder (18 people)
  • Insomnia (14 people)
  • Anxiety (13 people)
  • Psychotic Disorder (12 people)

Top co-used drugs for these people *:

  • Zoloft (22 people)
  • Cymbalta (20 people)
  • Paxil (17 people)
  • Prozac (16 people)
  • Effexor (15 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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