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Review: could Seroquel cause Serotonin syndrome?

Summary: Serotonin syndrome could be caused by Seroquel, especially for people who are female, 40-49 old, have been taking the drug for < 1 month, also take Zoloft, and have Depression.

We study 76,092 people who have side effects while taking Seroquel from FDA and social media. Among them, 172 have Serotonin syndrome. Find out below who they are, when they have Serotonin syndrome and more.

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On Apr, 14, 2014: 76,092 people reported to have side effects when taking Seroquel. Among them, 172 people (0.23%) have Serotonin Syndrome. They amount to 0.50% of all the 34,369 people who have Serotonin Syndrome on eHealthMe.

Trend of Serotonin syndrome in Seroquel reports

Time on Seroquel when people have Serotonin syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Serotonin syndrome59.57%19.15%10.64%2.13%8.51%0.00%0.00%

Gender of people who have Serotonin syndrome when taking Seroquel * :

FemaleMale
Serotonin syndrome70.23%29.77%

Age of people who have Serotonin syndrome when taking Seroquel * :

0-12-910-1920-2930-3940-4950-5960+
Serotonin syndrome0.00%0.00%3.72%10.11%12.77%32.45%25.53%15.43%

Severity of Serotonin syndrome when taking Seroquel ** :

leastmoderateseveremost severe
Serotonin syndrome0.00%100.00%0.00%0.00%

How people recovered from Serotonin syndrome ** :

n/a

Top conditions involved for these people * :

  1. Depression (85 people, 49.42%)
  2. Insomnia (33 people, 19.19%)
  3. Anxiety (31 people, 18.02%)
  4. Major depression (24 people, 13.95%)
  5. Psychotic disorder (24 people, 13.95%)

Top co-used drugs for these people * :

  1. Zoloft (49 people, 28.49%)
  2. Lithium carbonate (39 people, 22.67%)
  3. Cymbalta (31 people, 18.02%)
  4. Effexor (29 people, 16.86%)
  5. Paxil (28 people, 16.28%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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  • From this study (2 years ago):

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