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Review: could Seroquel cause Tinnitus?

Summary: Tinnitus could be caused by Seroquel, especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months, also take Clonazepam, and have Bipolar disorder.

We study 76,092 people who have side effects while taking Seroquel from FDA and social media. Among them, 200 have Tinnitus. Find out below who they are, when they have Tinnitus and more.

On Apr, 10, 2014: 75,979 people reported to have side effects when taking Seroquel. Among them, 205 people (0.27%) have Tinnitus. They amount to 0.18% of all the 112,935 people who have Tinnitus on eHealthMe.

Trend of Tinnitus in Seroquel reports

Time on Seroquel when people have Tinnitus * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Tinnitus when taking Seroquel * :


Age of people who have Tinnitus when taking Seroquel * :


Severity of Tinnitus when taking Seroquel ** :

leastmoderateseveremost severe

How people recovered from Tinnitus ** :

while on the drugafter off the drugnot yet

Top conditions involved for these people * :

  1. Bipolar disorder (96 people, 46.83%)
  2. Depression (78 people, 38.05%)
  3. Sleep disorder (45 people, 21.95%)
  4. Schizophrenia (39 people, 19.02%)
  5. Anxiety (35 people, 17.07%)

Top co-used drugs for these people * :

  1. Clonazepam (106 people, 51.71%)
  2. Paxil (102 people, 49.76%)
  3. Trazodone hcl (86 people, 41.95%)
  4. Meclizine (85 people, 41.46%)
  5. Hydrochlorothiazide (84 people, 40.98%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Seroquel, Tinnitus

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On eHealthMe, Seroquel (quetiapine fumarate) is often used for bipolar disorder. Find out below the conditions Seroquel is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Seroquel used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 months ago):

  • constant humming sound. I thought it was my pipes or my heater. Now I think it's tinnitus and just did a search to see if seroquel can cause it and it can.


  • From this study (1 year ago):

  • After restarting with quetiapine I had severe tinnitis last night. Know i don't know what to do. Stop with the quetiapine?


  • From this study (1 year ago):

  • Have severe ringing, buzzing in one ear for 6 weeks now. Had MRI of brain and ear, nothing wrong. Went to ENT, had hearing checked, he could find nothing but a healthy ear. Said I have tinnitus or Minnears Disease. I read about drug interactions. I am wondering if its possible this could be it. I am climbing the walls with this noise in my head.


    Susan on Oct, 14, 2012:

    I was taking Singulair for approximately 3 weeks. I developed sharp, intermittent pain in my right ear as well as tinnitus. After seeing an ENT who saw nothing but a healthy ear, he asked about any recent medications. I mentioned Singulair and decided to stop this medication immediately. I have been off the medication for approximately 2 weeks and the tinnitus has not gone away. My gut feeling is that I will be left with this terrible side effect the rest of my life.


    wisee on Oct, 27, 2012:

    I am 63 was taking citalopram and have ringing in one ear for the last 3-6 months. I also take Trileptal for seizures. Had low sodium during chemotherapy and might have got the ringing when sodium increased to normal range (took pill to increase sodium).
    Having bad reaction to Xanax taken off and on right now that took for depression.


    Craigm on Oct, 30, 2012:

    Is it serequel you are taking. I have been trying to come off of 50 mg xr. After 2 days the ringing is so so terrible I just can't stand it. By day 5 I just can not
    Put up with it so I take another seroquel. Good for two more days after that the ringing starts again.


    Andy on Nov, 2, 2012:

    Same story here. Started taking etodolac oct 2010 for back pain. I was using it sporadically whenever pain acted up. Earlier this year tinnitus started in one ear and has not stopped since- constant ringing 24/7. Had CT/MRI scan and exam - nothing wrong. Ringing gets so loud it wakes me up and prevents me from sleeping. Absolutely maddening. Anyhow I am pretty convinced now that the ringing was triggered
    by the etodolac. Thing is if I stop taking it the ringing persist so I am really at a loss. I did Xanax for the tinnitus but that did not help any bit.


    Craig on Nov, 3, 2012:

    are you having ringing coming off of serequel. You an contact me at
    This will absolutely drive you crazy. I don't mind anyone talking to me about this. Seroquel is an evil drug. I was on it then I was off but now I have new information to help come off. Of course it is free. I just want to help cause I know how bad it is. God Bless all of y'all that is going through this but you may not have too. Just put bad drug in the subject line.


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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