Review: could Simvastatin cause Anal Fissure?


Anal fissure is found among people who take Simvastatin, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Carvedilol, and have Renal failure chronic . We study 86,881 people who have side effects while taking Simvastatin from FDA and social media. Among them, 111 have Anal fissure. Find out below who they are, when they have Anal fissure and more.

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Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 85,176 users)

Anal Fissure

Anal fissure has been reported by people with hypotension, crohn's disease, diarrhea, fever, impaired healing (latest reports from 2,228 Anal fissure patients).

On Aug, 17, 2016

86,881 people reported to have side effects when taking Simvastatin.
Among them, 111 people (0.13%) have Anal Fissure

Number of reports submitted per year:

Could Simvastatin cause Anal fissure?

Time on Simvastatin when people have Anal Fissure *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anal Fissure when taking Simvastatin *:

  • female: 93.64 %
  • male: 6.36 %

Age of people who have Anal Fissure when taking Simvastatin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.93 %
  • 40-49: 0.93 %
  • 50-59: 2.8 %
  • 60+: 95.33 %

Severity if Anal Fissure when taking Simvastatin **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Renal Failure Chronic (98 people)
  • Vitamin Supplementation (1 person)
  • Healthy Living (1 person)
  • Blood Cholesterol Abnormal (1 person)
  • Bipolar Disorder (1 person)

Top co-used drugs for these people *:

  • Lisinopril (99 people)
  • Furosemide (99 people)
  • Digoxin (99 people)
  • Carvedilol (99 people)
  • Allopurinol (98 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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