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Review: could Simvastatin cause Anxiety (Stress and anxiety)?





Summary: Anxiety is found among people who take Simvastatin, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Aspirin, and have Hypertension.

We study 77,477 people who have side effects while taking Simvastatin from FDA and social media. Among them, 2,305 have Anxiety. Find out below who they are, when they have Anxiety and more.

You are not alone: join a mobile support group for people who take Simvastatin and have Anxiety >>>

Simvastatin

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 80,812 users)

Anxiety

Anxiety has been reported by people with depression, stress and anxiety, quit smoking, multiple sclerosis, pain.(latest reports from Anxiety 197,075 patients)

On Nov, 25, 2014: 77,462 people reported to have side effects when taking Simvastatin. Among them, 2,358 people (3.04%) have Anxiety.

Trend of Anxiety in Simvastatin reports

Time on Simvastatin when people have Anxiety * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anxiety27.16%20.37%11.73%8.02%22.84%2.47%7.41%

Age of people who have Anxiety when taking Simvastatin * :

0-12-910-1920-2930-3940-4950-5960+
Anxiety0.04%0.00%0.13%0.99%3.18%12.38%31.61%51.66%

Severity of Anxiety when taking Simvastatin ** :

leastmoderateseveremost severe
Anxiety2.86%65.71%28.57%2.86%

How people recovered from Anxiety ** :

while on the drugafter off the drugnot yet
Anxiety5.88%11.76%82.35%

Top conditions involved for these people * :

  1. Hypertension (496 people, 21.03%)
  2. Smoking cessation therapy (309 people, 13.10%)
  3. Blood cholesterol increased (290 people, 12.30%)
  4. Depression (265 people, 11.24%)
  5. Blood cholesterol (248 people, 10.52%)

Top co-used drugs for these people * :

  1. Aspirin (819 people, 34.73%)
  2. Zocor (543 people, 23.03%)
  3. Lisinopril (504 people, 21.37%)
  4. Zometa (452 people, 19.17%)
  5. Prilosec (440 people, 18.66%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Anxiety while taking Simvastatin?

You are not alone! Join a mobile support group:
- support group for people who take Simvastatin and have Anxiety
- support group for people who take Simvastatin
- support group for people who have Anxiety

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Can you answer these questions (Ask a question):

  • Does doxepin cause abdominal adhesions?
    (Asked by a 73 year old man who has Anxiety)
    Have had adhesions and still taking doxepin. Need the doxepin, but worry about more adhesions
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    (Asked by a 34 year old woman who has Muscle Tightness, Muscle Contractions Involuntary, Ptsd, Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, Tension, Anxiety Disorder, Depression, Bulimia, Exhaustion, Fatigue, Lethargy, Tiredness, Weariness, ADHD, and takes Nuvigil, Prozac, Flexeril, Topamax, Xanax, Adderall 30)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Will taking simvistatin for dyslipidemia for 5 yrs cause my liver to ache/hurt?
    (Asked by a 62 year old woman who has Back Pain, Side Pain, and takes Simvastatin)
    Been taking simvastatin for about 5 yrs, but in the last 2-3 months have been experiencing ache and sometimes pain from my lower right front emanating around my right side and into my lower back, I have been tested for a possible urinary tract infection that came in negative, doctors are unsure of what could be going on at this point, I am suspicious of the simvastatin affecting my liver but am not sure because of the long time I have been using it and not experiencing any problem until now
  • Can i take my ativan if i'm taking phenteremine? (1 answer)
    (Asked by a 40 year old woman who has Anxiety, and takes Ativan)
    I just started taking phenteremine and I can't sleep. I take it at 6 am
    Am I able to take an Ativan at bed time?
  • When was this study made? can i sue merck?
    (Asked by a 63 year old woman who has Coma, Aneurysm In The Brain, and takes Simvastatin)
    I had a cerebral hemmorage and stroke. Was lucky and was at a major casino in Las Vegas. I had surgery through my groin to stop the bleed. I was then left in a coma for 2 months. When I started to wake up I could not move, eat, swallow, I did not know who I was or who my husband of 40 years were. I had to be taught everything over again. I had intense therapy. Physical, speech, cognitive, etc. It was over a year before I caught swallow soft food under supervision. Over a year before I was able to learn how to transfer from my bed to a wheelchair. I lost over 2 years of my life. I am now still recovery but I do have a quality of life that they told me I would never have. I was 2 weeks before my 60 birthday and the only drug I every took was Simvastian. Which was a very common drug I thought was harmless. My story was even published in my local newspaper.

    CAN WE FORM A CLASS ACTION SUIT???

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  • A life of depression and fatigue
    (Posted by a 70 year old man who has COPD, PTSD, Chronic Fatigue Syndrome, Dysthymia, and takes Simvastatin, Daytrana, Klonopin, Concerta, Lamictal Xr, Prozac)
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
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    (Posted by a 60 year old man who has Anxiety, and takes Xanax)
    I am wondering if zopocline is compatible with Xanax. I have taken the together and had no adverse effects. Has any had this experience?
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    (Posted by a 55 year old man who has Anxiety, Panic Attack, Insomnia, and takes Lipitor)
    My doctor put me on generic lipitor my triglycerides were slightly high 158 vs 150 goal and cholesterol not bad 128/28 although my ratio is bad. After less than a week on the medicine I woke up at 3 am wide awake and unable to calm down. I had anxiety issues several years go but have been off the meds for several years, I have a lot on my mind, aging parents and mother in law, kids in college that are struggling, my wife and I are 55 in corporate America, getting pushed aside, what to do in retirement, etc..but I was keeping it all together. I have incredibly anxious since that night. Still waking up at 3 am every night. Initially lots of thoughts about my loved ones dying. Thoughts about either my wife or I living alone, these thoughts have faded. None of the issues are on my mind but I get crazy anxious and cannot be alone. I am able to fall asleep, actually fall out really hard. Wake up every night at 3 and end up very anxious by noon. No appetite, lost more than 10 lbs in 10 days. On some meds to calm down and back on the anxiety meds. I believe the Lipitor triggered the attacks. I stopped the Lipitor immediately.
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    (Posted by a 55 year old man who has Swelling Of The Ankles - Feet - Legs, and takes Simvastatin, Cetirizine Hydrochloride Allergy, Amitriptyline Hydrochloride, Venlafaxine Hydrochloride, Morphine Sulfate, Amlodipine Besylate)
    Severe swelling in legs, ankles and feet after being on my feet for more than one hour. Pain in calves and ankles. Feels like they're being squeezed or compressed. Pain dissipates after laying down for a few hours. Swelling never completely dissipates. Always some swelling in ankles.
  • Prednisone side effects (1 response)
    (Posted by a 25 year old woman who has Headache, Anxiety, Heartburn, Blurred Vision, Nausea, and takes Prednisone)
    Took this for 6 days, tapering at the end to treat a rash caused by a spider bite. The heartburn started on day 1 but the other symptoms didn't begin until day 4. None we're severe but they weren't fun either. The blurred vision was worst.

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