Review: could Simvastatin cause Arthritis?


Arthritis is found among people who take Simvastatin, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Aspirin, and have Hypertension . We study 75,672 people who have side effects while taking Simvastatin from FDA and social media. Among them, 529 have Arthritis. Find out below who they are, when they have Arthritis and more.

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Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 78,207 users)


Arthritis (form of joint disorder that involves inflammation of one or more joints) has been reported by people with breathing difficulty, high blood pressure, stroke, chest pain, stress and anxiety (latest reports from 52,269 Arthritis patients).

On Jul, 28, 2016

75,672 people reported to have side effects when taking Simvastatin.
Among them, 529 people (0.7%) have Arthritis

Number of reports submitted per year:

Could Simvastatin cause Arthritis?

Time on Simvastatin when people have Arthritis *:

  • < 1 month: 2.78 %
  • 1 - 6 months: 16.67 %
  • 6 - 12 months: 5.56 %
  • 1 - 2 years: 11.11 %
  • 2 - 5 years: 16.67 %
  • 5 - 10 years: 30.56 %
  • 10+ years: 16.67 %

Gender of people who have Arthritis when taking Simvastatin *:

  • female: 63.85 %
  • male: 36.15 %

Age of people who have Arthritis when taking Simvastatin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.72 %
  • 40-49: 7.4 %
  • 50-59: 28.16 %
  • 60+: 63.72 %

Severity if Arthritis when taking Simvastatin **:

  • least: 0.0 %
  • moderate: 28.57 %
  • severe: 42.86 %
  • most severe: 28.57 %

How people recovered from Arthritis **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Hypertension (111 people)
  • Blood Cholesterol (85 people)
  • Diabetes Mellitus (81 people)
  • Blood Cholesterol Increased (74 people)
  • Mental Disorder (51 people)

Top co-used drugs for these people *:

  • Aspirin (127 people)
  • Zocor (106 people)
  • Prilosec (102 people)
  • Nitroglycerin (91 people)
  • Toprol-Xl (84 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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