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Review: could Simvastatin cause Gout?

Summary: Gout could be caused by Simvastatin, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Aspirin, and have Hypertension.

We study 77,270 people who have side effects while taking Simvastatin from FDA and social media. Among them, 271 have Gout. Find out below who they are, when they have Gout and more.

On Apr, 16, 2014: 77,270 people reported to have side effects when taking Simvastatin. Among them, 271 people (0.35%) have Gout. They amount to 0.48% of all the 56,507 people who have Gout on eHealthMe.

Trend of Gout in Simvastatin reports

Time on Simvastatin when people have Gout * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Gout41.18%5.88%11.76%2.94%2.94%29.41%5.88%

Age of people who have Gout when taking Simvastatin * :

0-12-910-1920-2930-3940-4950-5960+
Gout0.00%0.00%0.00%0.00%2.62%8.73%19.65%69.00%

Severity of Gout when taking Simvastatin ** :

leastmoderateseveremost severe
Gout0.00%27.27%63.64%9.09%

How people recovered from Gout ** :

while on the drugafter off the drugnot yet
Gout0.00%40.00%60.00%

Top conditions involved for these people * :

  1. Hypertension (46 people, 16.97%)
  2. Gout (33 people, 12.18%)
  3. Diabetes mellitus (30 people, 11.07%)
  4. Multiple myeloma (24 people, 8.86%)
  5. Hyperlipidaemia (23 people, 8.49%)

Top co-used drugs for these people * :

  1. Aspirin (94 people, 34.69%)
  2. Allopurinol (85 people, 31.37%)
  3. Furosemide (57 people, 21.03%)
  4. Digoxin (40 people, 14.76%)
  5. Omeprazole (39 people, 14.39%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Simvastatin, Gout

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On eHealthMe, Simvastatin (simvastatin) is often used for high blood cholesterol. Find out below the conditions Simvastatin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Simvastatin used for and how effective is it:

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Could your condition cause it?

Comments from related studies:

  • From this study (7 months ago):

  • Lung function tests outcome - OK for someone with Primary Sjogrens Syndrome. Sprirometery Tests - 320 (normal between 300 - 400) GP told me. Hypoxia diagnosed when I went for pre-op testing and again after op. GP told me everything was normal.
    After knee arthroscopy recently - surgeon told me I had chondro-calcinosis (Pseudogout). Now Rheumatologist has informed me that I have real Gout. He is thinking now about putting me on another drug! Nurse Specialist has suggested Iloprost Infusion - yet another drug. I meet none of the risk factors for gout so I am wondering if I am experiencing side effects from the other drugs I am on. I work for the NHS full time and have to for some years to come as I am the only breadwinner. Thanks for your website - very informatve. Kind regards. Chris Kirwan (Mrs)

    Reply

  • From this study (1 year ago):

  • Moved from baby Aspirin to full strength after suffering double vision. Double vision went away in time, and who is to know if the full strength dose prevents it recurring? Simvastatin was already being taken. This week I had a flare-up of gout in my right toe, something I haven't experienced since I gave up alcohol some 25 years ago. I'm thinking of stopping the Simvastatin and reducing the aspirin to the baby dose again.

    Reply

  • From this study (2 years ago):

  • suffer with osteoarthritis in knees and feet

    Reply

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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