Review: could Simvastatin cause Kidney Failure?


Kidney failure is found among people who take Simvastatin, especially for people who are male, 60+ old , have been taking the drug for 1 - 6 months, also take medication Aspirin, and have Hypertension . We study 93,793 people who have side effects while taking Simvastatin from FDA and social media. Among them, 1,809 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

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Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 94,390 users)

Kidney Failure

Kidney failure (loss of kidney function) has been reported by people with breathing difficulty, hypotension, renal failure acute, acute kidney failure, diarrhea (latest reports from 62,612 Kidney failure patients).

On Aug, 19, 2016

93,793 people reported to have side effects when taking Simvastatin.
Among them, 1,809 people (1.93%) have Kidney Failure

Number of reports submitted per year:

Could Simvastatin cause Kidney failure?

Time on Simvastatin when people have Kidney Failure *:

  • < 1 month: 15.6 %
  • 1 - 6 months: 28.37 %
  • 6 - 12 months: 7.09 %
  • 1 - 2 years: 12.77 %
  • 2 - 5 years: 12.06 %
  • 5 - 10 years: 18.44 %
  • 10+ years: 5.67 %

Gender of people who have Kidney Failure when taking Simvastatin *:

  • female: 37.58 %
  • male: 62.42 %

Age of people who have Kidney Failure when taking Simvastatin *:

  • 0-1: 0.0 %
  • 2-9: 0.06 %
  • 10-19: 0.51 %
  • 20-29: 0.58 %
  • 30-39: 2.12 %
  • 40-49: 5.06 %
  • 50-59: 16.86 %
  • 60+: 74.74 %

Severity if Kidney Failure when taking Simvastatin **:

  • least: 33.33 %
  • moderate: 33.33 %
  • severe: 33.33 %
  • most severe: 0.0 %

How people recovered from Kidney Failure **:

  • while on drug: 33.33 %
  • after off the drug: 33.33 %
  • not yet: 33.33 %

Top conditions involved for these people *:

  • Hypertension (284 people)
  • Hypercholesterolaemia (131 people)
  • Coronary Artery Bypass (124 people)
  • Diabetes Mellitus (96 people)
  • Type 2 Diabetes Mellitus (89 people)

Top co-used drugs for these people *:

  • Aspirin (472 people)
  • Furosemide (308 people)
  • Lasix (281 people)
  • Lisinopril (275 people)
  • Omeprazole (245 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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