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Review: could Simvastatin cause Kidney stones?

Summary: Kidney stones could be caused by Simvastatin, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take Aspirin, and have Hypertension.

We study 77,270 people who have side effects while taking Simvastatin from FDA and social media. Among them, 282 have Kidney stones. Find out below who they are, when they have Kidney stones and more.

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Simvastatin

Simvastatin (latest outcomes from 80,585 users) has active ingredients of simvastatin. It is often used in high blood pressure.

Kidney stones

Kidney stones (latest reports from 105,306 patients) has been reported by people with multiple sclerosis, osteoporosis, high blood pressure, rheumatoid arthritis, pain.

On Apr, 11, 2014: 77,313 people reported to have side effects when taking Simvastatin. Among them, 282 people (0.36%) have Kidney Stones. They amount to 0.27% of all the 105,112 people who have Kidney Stones on eHealthMe.

Trend of Kidney stones in Simvastatin reports

Time on Simvastatin when people have Kidney stones * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Kidney stones55.56%11.11%0.00%0.00%33.33%0.00%0.00%

Age of people who have Kidney stones when taking Simvastatin * :

0-12-910-1920-2930-3940-4950-5960+
Kidney stones0.00%0.00%0.00%0.00%3.98%14.60%36.28%45.13%

Severity of Kidney stones when taking Simvastatin ** :

n/a

How people recovered from Kidney stones ** :

n/a

Top conditions involved for these people * :

  1. Hypertension (45 people, 15.96%)
  2. Blood cholesterol increased (38 people, 13.48%)
  3. Multiple myeloma (37 people, 13.12%)
  4. Osteoporosis (28 people, 9.93%)
  5. Metastases to bone (24 people, 8.51%)

Top co-used drugs for these people * :

  1. Aspirin (94 people, 33.33%)
  2. Zometa (76 people, 26.95%)
  3. Omeprazole (58 people, 20.57%)
  4. Lipitor (48 people, 17.02%)
  5. Coumadin (48 people, 17.02%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Simvastatin, Kidney stones

You can also:

On eHealthMe, Simvastatin (simvastatin) is often used for high blood pressure. Find out below the conditions Simvastatin is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Simvastatin used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (6 days ago):

  • For the last year I seem to be bruising a lot easier and any cut I get takes for ever to heal. My kitten scratched me the other day and I had to wrap my hand to get to a sink to put it under water and try to make the bleeding stop. I wrapped it completely in guaze to make it stop. It actually scared me to see so much blood from a cat scratch! It looked like someone had been stabbed. The next day my hand swelled up and bruised like it had been hit with a hammer!

    Reply

  • From this study (1 week ago):

  • Left kidney pain for several days with a marked inability to urinate & a significant amount of blood in my urine

    Reply

  • From this study (1 week ago):

  • BECAUSE OF A STROKE I EXPERIENCED AUGUST 5, 2010, I AM UNCOMFORTABLE IN MY OWN SKIN 24/7 ADD THE DISCOMFORTS CREATED FROM THE MEDICINE I TAKE SOME DAYS ARE HARDER TO STAY POSITIVE ABOUT MY LIFE. I HAVE A LOT OF STRESS DAILY AND TRYING TO FIGURE OUT HOW TO ACHIEVE SOME LEVEL OF COMFORT AND I SEEM TO BE FAILING AND I FEEL ITS DUE TO THE COMBINATION OF THE MEDICINES I TAKE.

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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