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Review: could Simvastatin cause Kidney failure (Acute kidney failure)?

Summary: Kidney failure is found among people who take Simvastatin, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months, also take medication Aspirin, and have High blood pressure.

We study 77,518 people who have side effects while taking Simvastatin from FDA and social media. Among them, 1,760 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

You are not alone: join a mobile support group for people who take Simvastatin and have Kidney failure >>>

 

 

 

 

Simvastatin

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from 80,864 Simvastatin users)

Kidney failure

Kidney failure (loss of kidney function) has been reported by people with high blood pressure, coronary artery bypass, multiple myeloma, diabetes, pain. (latest reports from 57,659 Kidney failure patients)

On Feb, 6, 2015: 77,499 people reported to have side effects when taking Simvastatin. Among them, 1,660 people (2.14%) have Kidney Failure.

Trend of Kidney failure in Simvastatin reports

Time on Simvastatin when people have Kidney failure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Kidney failure15.83%27.34%5.04%15.83%9.35%20.14%6.47%

Age of people who have Kidney failure when taking Simvastatin * :

0-12-910-1920-2930-3940-4950-5960+
Kidney failure0.00%0.00%0.46%0.20%1.92%4.84%17.50%75.08%

Severity of Kidney failure when taking Simvastatin ** :

leastmoderateseveremost severe
Kidney failure33.33%33.33%33.33%0.00%

How people recovered from Kidney failure ** :

while on the drugafter off the drugnot yet
Kidney failure50.00%0.00%50.00%

Top conditions involved for these people * :

  1. Hypertension (259 people, 15.60%)
  2. Hypercholesterolaemia (129 people, 7.77%)
  3. Diabetes mellitus (95 people, 5.72%)
  4. Type 2 diabetes mellitus (94 people, 5.66%)
  5. Atrial fibrillation (67 people, 4.04%)

Top co-used drugs for these people * :

  1. Aspirin (555 people, 33.43%)
  2. Furosemide (291 people, 17.53%)
  3. Lasix (279 people, 16.81%)
  4. Lisinopril (245 people, 14.76%)
  5. Omeprazole (224 people, 13.49%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of simvastatin and kidney failure on

Do you have Kidney Failure while taking Simvastatin?

You are not alone! Join a mobile support group:
- support group for people who take Simvastatin and have Kidney Failure
- support group for people who take Simvastatin
- support group for people who have Kidney Failure

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • Sciatica caused from simvastatin
    My mom was prescribed simvastatin to reduce her cholesterol. Within a couple of weeks taking it she complained about muscle pain in her back to her doc. Doc said it was normal. She continued to take the statin until the pain moved down her leg to her calf. She had a blood test and the doc told her to stop taking it. She did but the pain is still there (more than a year).
    My mom believes her sciatic pain is directly related to her use of the statin.
    She's been off it for more than a year. Has the statin permanently damaged her?
    What can she do besides the PT that she has been doing?
    Thanks.
  • What are the medicines you can take for a cold or/and flu who is taking pradaxa?
    I am taking all of the meds listed especially the newest drug, Pradaxa, which my Primary Doctor knows nothing about. He said since it is new there is no data out there on other medicines you can use with Pradaxa. I have now got the Flu and he doesn't know of any medication I can take with me taking Pradaxa. What am I to do, just die? Does anyone out there that is taking Pradaxa and had the Flu or even a cold what medication did you take for flu and/or cold? PLEASE WILL SOMEBODY HELP ME!
  • I took a musinex dm and acetominphen for congestion and a headache and fainted shortly after.
    I have fainted a few years ago and was told it was probably due to dehydration due to a couple glasses of wine and being hot. This incident was after breakfast and no wine!
  • Can i take a steroid while taking xarelto (1 answer)
    I took prednisone for constant cough. had 3rd surgery on back one year ago. Had to patch spinal cord. Got blood clots. Had pulmonary embolism. Now have severe bronchitis. I know the prednisone will take care of cough, but what else?
  • How many/what percentage of older males who have had a stroke, have another while taking uloric?
    Concerned as my Rheumatologist wants me to start using Uloric40 mg and while I see that their is a relatively small incidence of stroke occurring (unless you are part of the "small" group); I have been unable to locate statistics for those previous stroke patients that are now using or have used Uloric, and had another stroke.

More questions for: Simvastatin, Kidney failure

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    In my fifth year of living with my ex-boyfriend, he began taking Effexor and soon developed urinary incontinence, kidney failure and nightmares or night terrors so severe that he frequently screamed for prolonged periods, flailed and threw punches in his sleep. Upon ceasing to take Effexor, his sleep returned to normal. His kidneys also recovered, and he regained the ability to control urination. About a year after that, he was arrested for downloading child pornography, and I haven't spoken to him since. I'm not suggesting that Effexor caused him to become a pedophile, but it has been noted to produce personality changes in some users. It would be hard to ascertain whether any or all of these side effects resulted from the drug, but I would NEVER take it or allow anyone I cared about to do so. He had never exhibited any such symptoms before taking it, and I feel it ruined his life on many levels.
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More reviews for: Simvastatin, Kidney failure

Comments from related studies:

  • From this study (2 years ago):

  • LOA/13 on Mar, 27, 2013:

    Female, 57yrs, Bipolar, looking for any comments with reference to interation of the following daily dosage drugs and the introduction of Lamotrigine to my dialy regiment.
    Seroquel 800mg, Metforin 2000mg, Vimovo 500/40mg, Tylenol 2000mg. My Doc now would like to introduce Lamotrigine as a counter measure to my mood swings.
    Does anyone have comments of the interation of these 4 drugs with Lamotrigine?
    Your current and introductional experiences of this drug is appreciated. Thanks

    Reply

    LOA/13 on Mar, 27, 2013:

    Hi Marie L,
    I am also a female 57yrs, and have been trying to manage my Bipolar since my very early years. I like you, had surgery and because it was emergency surgery, no one had my medical records. At that time I was taking Lithium, the outcome was sever infection which took over 8mos to counteract. I appreciate your candor with your disclosure, because up until now (15 years later) I was only told the infection was due to the nature of the surgery (being emergency). Which I concluded, it was my fault for the outcome. I always thought the surgeons simplistic reasoning for the infection was a means by which to not have to fully disclaim the actual Reason = Lithium in my blood stream. I required another surgery for a broken arm (six places), which was postpone for several weeks. Now it makes sence for the postponement, he wanted to make sure the Lithium was out of my blood prior. This other surgery went off without a hitch. When and were possible, I highly recommend people to wear Medic Alert Bracelets, listing the medications you are taking. Thanks for listening.

    Reply

    Marie L on Jun, 20, 2012:

    I am a 54-year-old Caucasian woman who recently underwent removal of a benign brain tumor via general anesthetic. Although I advised the anesthesia staff that I had been taking lithium for about 30 years, at the time of my surgery, I didn't know that lithium should be discontinued at least 72 hours to two weeks before surgery to avoid dehydration and resulting diabetes insipidis (abnormal urination)which is known to cause blindness. After my surgery, I was unable to be awakened and went into a "metabolic encephalopathy" for about three weeks. When I woke up, I was blind in my right eye. According to my neurosurgeon, the reason for the coma was due to lithium being in my system. As a result, I have total, irreversible blindness in my right eye. My surgeon's position is that it was not from the surgery and, instead, the medical staff had to wait until the lithium was flushed out of my body. This NEVER should have happened. My sodium levels sky-rocketed along with my blood pressure and blood sugar. If I would have known all of this before surgery, I would not have taken my lithium for the prescribed amount of time and definitely would have advised the doctor and medical staff accordingly. If you are taking lithium and have a general anesthesia scheduled, be sure to advise your surgeon and the anesthesia staff that you want to discontinue lithium until after the surgery when your vital signs are stable. Good luck to you.

    Reply

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