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Review: could Sinemet cause Dyskinesia?

Summary: Dyskinesia could be caused by Sinemet, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take Sinemet cr, and have Parkinson's disease.

We study 10,370 people who have side effects while taking Sinemet from FDA and social media. Among them, 422 have Dyskinesia. Find out below who they are, when they have Dyskinesia and more.

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Sinemet (latest outcomes from 11,024 users) has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease, restless leg syndrome. Commonly reported side effects of Sinemet include fall, weakness, parkinson's disease, fatigue, hallucinations.


Dyskinesia (abnormality or impairment of voluntary movement) (latest reports from 88,467 patients) has been reported by people with depression, parkinson's disease, pain, bipolar disorder, high blood pressure.

On Apr, 11, 2014: 10,370 people reported to have side effects when taking Sinemet. Among them, 422 people (4.07%) have Dyskinesia. They amount to 0.48% of all the 88,072 people who have Dyskinesia on eHealthMe.

Trend of Dyskinesia in Sinemet reports

Time on Sinemet when people have Dyskinesia * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years

Gender of people who have Dyskinesia when taking Sinemet * :


Age of people who have Dyskinesia when taking Sinemet * :


Severity of Dyskinesia when taking Sinemet ** :

leastmoderateseveremost severe

How people recovered from Dyskinesia ** :


Top conditions involved for these people * :

  1. Parkinson's disease (257 people, 60.90%)
  2. Depression (41 people, 9.72%)
  3. Dyskinesia (19 people, 4.50%)
  4. Anxiety (17 people, 4.03%)
  5. Parkinsonism (13 people, 3.08%)

Top co-used drugs for these people * :

  1. Sinemet cr (117 people, 27.73%)
  2. Comtan (101 people, 23.93%)
  3. Tasmar (86 people, 20.38%)
  4. Mirapex (70 people, 16.59%)
  5. Requip (64 people, 15.17%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Sinemet, Dyskinesia

You can also:

On eHealthMe, Sinemet (carbidopa; levodopa) is often used for parkinson's disease. Find out below the conditions Sinemet is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Sinemet used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (2 years ago):

  • Laa on Jul, 28, 2012:

    Female 68 years old taking neupro patch 2 weeks and 4 have fallen off, also take sinamet azilect and stopping requip. Feel miserable have had pd 12 hrs any help,,,


  • From this study (3 years ago):

  • Valerie on Jun, 29, 2011:

    I'm 58 years old, female and started taking tiny doses of Sinemet 10/100 (1/2 tab daily) six months ago. Much of my gray hair has grown out brown. My thick, fast growing mane used to need coloring once a week to prevent the appearance of an obvious "skunk streak" but since using Sinemet, I only need color my hair every 4 to 6 weeks. My hair is still growing as fast as before requiring frequent trimming.


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related study

- Sinemet side effects


Related symptom

- Dyskinesia



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