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Review: could Sinemet cause Restless leg syndrome?

Summary: Restless leg syndrome could be caused by Sinemet, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Requip, and have Restless legs syndrome.

We study 10,370 people who have side effects while taking Sinemet from FDA and social media. Among them, 72 have Restless leg syndrome. Find out below who they are, when they have Restless leg syndrome and more.

On Apr, 11, 2014: 10,370 people reported to have side effects when taking Sinemet. Among them, 72 people (0.69%) have Restless Leg Syndrome. They amount to 0.11% of all the 67,330 people who have Restless Leg Syndrome on eHealthMe.

Trend of Restless leg syndrome in Sinemet reports

Time on Sinemet when people have Restless leg syndrome * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Restless leg syndrome16.67%0.00%0.00%0.00%66.67%16.67%0.00%

Gender of people who have Restless leg syndrome when taking Sinemet * :

FemaleMale
Restless leg syndrome54.22%45.78%

Age of people who have Restless leg syndrome when taking Sinemet * :

0-12-910-1920-2930-3940-4950-5960+
Restless leg syndrome0.00%0.00%0.00%0.00%1.72%5.17%41.38%51.72%

Severity of Restless leg syndrome when taking Sinemet ** :

leastmoderateseveremost severe
Restless leg syndrome0.00%0.00%0.00%100.00%

How people recovered from Restless leg syndrome ** :

while on the drugafter off the drugnot yet
Restless leg syndrome0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Restless legs syndrome (33 people, 45.83%)
  2. Parkinson's disease (33 people, 45.83%)
  3. Sleep disorder (20 people, 27.78%)
  4. Depression (16 people, 22.22%)
  5. Bipolar disorder (15 people, 20.83%)

Top co-used drugs for these people * :

  1. Requip (41 people, 56.94%)
  2. Seroquel (31 people, 43.06%)
  3. Depakote (20 people, 27.78%)
  4. Lipitor (19 people, 26.39%)
  5. Mirapex (18 people, 25.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Sinemet, Restless leg syndrome

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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