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Review: could Spironolactone cause Breathing difficulty?

Summary: Breathing difficulty is found among people who take Spironolactone, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Furosemide, and have High blood pressure.

We study 25,366 people who have side effects while taking Spironolactone from FDA and social media. Among them, 1,898 have Breathing difficulty. Find out below who they are, when they have Breathing difficulty and more.

You are not alone: join a mobile support group for people who take Spironolactone and have Breathing difficulty >>>

 

 

 

 

Spironolactone

Spironolactone has active ingredients of spironolactone. It is often used in acne. (latest outcomes from 26,437 Spironolactone users)

Breathing difficulty

Breathing difficulty has been reported by people with high blood pressure, asthma, rheumatoid arthritis, pain, chronic obstructive pulmonary disease. (latest reports from 165,364 Breathing difficulty patients)

On Jan, 5, 2015: 25,356 people reported to have side effects when taking Spironolactone. Among them, 1,898 people (7.49%) have Breathing Difficulty.

Trend of Breathing difficulty in Spironolactone reports

Time on Spironolactone when people have Breathing difficulty * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Breathing difficulty34.02%5.15%24.74%9.28%19.59%7.22%0.00%

Age of people who have Breathing difficulty when taking Spironolactone * :

0-12-910-1920-2930-3940-4950-5960+
Breathing difficulty0.67%0.79%0.91%4.02%4.15%8.66%19.45%61.34%

Severity of Breathing difficulty when taking Spironolactone ** :

leastmoderateseveremost severe
Breathing difficulty7.69%38.46%53.85%0.00%

How people recovered from Breathing difficulty ** :

while on the drugafter off the drugnot yet
Breathing difficulty11.11%22.22%66.67%

Top conditions involved for these people * :

  1. Hypertension (174 people, 9.17%)
  2. Pulmonary arterial hypertension (121 people, 6.38%)
  3. Cardiac failure congestive (94 people, 4.95%)
  4. Chronic obstructive pulmonary disease (93 people, 4.90%)
  5. Pain (91 people, 4.79%)

Top co-used drugs for these people * :

  1. Furosemide (641 people, 33.77%)
  2. Digoxin (530 people, 27.92%)
  3. Aspirin (517 people, 27.24%)
  4. Lasix (494 people, 26.03%)
  5. Lisinopril (303 people, 15.96%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Breathing Difficulty while taking Spironolactone?

You are not alone! Join a mobile support group:
- support group for people who take Spironolactone and have Breathing Difficulty
- support group for people who take Spironolactone
- support group for people who have Breathing Difficulty

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • I suffer from hypotension after taking meal along with breathlessness and itching
    after eating I fell as if I will faint n hav dyspnea n headache.. n if I try to walk then I hav severe itching all over the body ... if I don't take meal then I am fine
  • Kindly tell me whether this treatment is accurate for spine tb?
    have spinal tb and having treatment since 5 months..also a kidney dialysis patient..having two dialysis per week...i think this treatment is not effective because i am having severe back pain, severe pain in feet..nausea..and shortness of breath...
  • Number of dysponea reports for potassium chloride. jantoven medication
    Having serious bouts of shortness of breath, fatigue, disorientation with minimal exertion---doctor is not convinced symptoms are real.
  • Is there a published study that shows propranolol can cause shortness of breath and chest tightness?
    I am a pharmacy student in his final year on rotation at the VA Memorial Hospital. While working up a patient I noticed she has called many times complaining of "panic attacks" stating that she can't breath and has chest tightness. Over the previous two week I also noticed she has been to the ER for these same symptoms.

    Patient is a 61 year old female, with history of hypertension, dyslipidemia, migraine without aura, and while I don't see a specific diagnosis the patient current has a script for albuterol and at one time had a script for ipratropium. Patient has been a lifelone smoker who quit this past June.

    This patient was diagnosed with migraine headaches in 1986 and has been on propranolol 80mg ever since - 28 years. Interestingly, 1986 was around the time Inderal lost its patent and propranolol became generic.

    The patient served in the army from 1972-1976 during the vietnam war. She has a history of mental health issues (not sure what) and anxiety. I feel she has been "labeled" and current episodes of "panic attacks" are answered with benzodiazapines and she is sent on her way.

    During my first look into propranolol, the very first page said, "Check with your doctor immediately if you have any of the following side effects:
    1)Coughing up Mucus
    2)Shortness of Breath
    3)Tightness in the Chest"

    This caught my attention. I then started probing deeper and found an article written by Dr. Noreen Kassem titled "The Long Term Side Effects of Propranolol." In the article she wrote, "...propranolol and other beta blockers can also worsen breathing disorders, such as emphysema and asthma, because they constrict the air passageways of the lungs and can cause fluid build-up in the lungs. This can result in shortness of breath, difficulty breathing and chest tightness in patients who are on propranolol for long periods of time, or who have respiratory disorders."

    I tried to find Dr. Kassem to no avail. I wanted to know exactly where she got this information. I would like to find some primary literature on this topic but haven't had any luck. I need proof, because as of right now I'm a student being told that "she has been on this agent for 28 years, I doubt it's bothering her now." I'm not buying it and I think something is here.

    -61 year olf lifelone smoker with almost guaranteed declining lung function
    -28 year (chronic) use of propranlol (a non-selective beta blocker)
    -Possible asthmatic
    -Experiencing "shortness of breath" and "Chest tightness" that she and everyone else is called anxiety and/or panic attacks.

    I think the propranolol, while not the cause of these problems, is certainly exacerbating them. Does anyone have proof of this happening; peer reviewed articles, anything. My rotation is done in 2 weeks and I know no one will ever look into this again after I'm gone.

    ps... forgive any typos
  • Is it ok to take fioricet and albuterol together?
    I have been having bad headaches the pain is behind my eyes front for head and temples (I have also had a warming sensation in the back of head and thought body here and there that no one can explain to me ) but I have been subscribed fioricet but I'm a chronic asthmatic so I take albuterol inhaler and some times solution for my neb I read that these 2 can have interation and I been feeling shortness of breath which I know can be a side effect from fioricet but I do take my inhaler daily and I want to check if anyone has been in same situation and if there were any interactions

More questions for: Spironolactone, Breathing difficulty

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