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Review: could Spironolactone cause Hypothyroidism?

Summary: Hypothyroidism could be caused by Spironolactone, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Aspirin, and have Hypertension.

We study 25,278 people who have side effects while taking Spironolactone from FDA and social media. Among them, 111 have Hypothyroidism. Find out below who they are, when they have Hypothyroidism and more.

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On Apr, 10, 2014: 25,245 people reported to have side effects when taking Spironolactone. Among them, 111 people (0.44%) have Hypothyroidism. They amount to 0.09% of all the 128,022 people who have Hypothyroidism on eHealthMe.

Trend of Hypothyroidism in Spironolactone reports

Time on Spironolactone when people have Hypothyroidism * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Hypothyroidism0.00%62.50%12.50%25.00%0.00%0.00%0.00%

Age of people who have Hypothyroidism when taking Spironolactone * :

0-12-910-1920-2930-3940-4950-5960+
Hypothyroidism0.00%0.00%0.00%0.00%1.96%4.90%7.84%85.29%

Severity of Hypothyroidism when taking Spironolactone ** :

n/a

How people recovered from Hypothyroidism ** :

n/a

Top conditions involved for these people * :

  1. Hypertension (17 people, 15.32%)
  2. Cardiac failure (10 people, 9.01%)
  3. Tachycardia (8 people, 7.21%)
  4. Oedema (8 people, 7.21%)
  5. Neoplasm malignant (7 people, 6.31%)

Top co-used drugs for these people * :

  1. Aspirin (40 people, 36.04%)
  2. Digoxin (39 people, 35.14%)
  3. Furosemide (38 people, 34.23%)
  4. Lasix (36 people, 32.43%)
  5. Levothyroxine sodium (32 people, 28.83%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

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Related topic: Spironolactone, Hypothyroidism

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On eHealthMe, Spironolactone (spironolactone) is often used for acne. Find out below the conditions Spironolactone is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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Comments from related studies:

  • From this study (19 hours ago):

  • My endocrinologist /doctor has my fluid intake limited to 48 ounces of liquids per day (all liquids) because my sodium levels were off due to the drug spironolactone , I was taking 200 mg per day but have cut back to 100 mg per day for the last year.
    Also my Crestor dosage is 20 mg per day.

    Reply

  • From this study (3 weeks ago):

  • I also quit smoking last July and have put on a lot of weight and have not been able to lose it so far. I have also been dealing with a lot of depression and I am in perimenopause. I have been diagnosed with polycystic ovary syndrome by an endrocrine dr. but my obgyn does not agree with that diagnosis and neither do I.

    Reply

  • From this study (4 weeks ago):

  • Had echo gram and told I had pulmionary hypertension moderate to severe could any of these medicines be the cause

    Reply

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