Could Spironolactone cause Hypothyroidism - from FDA reports


Summary

Hypothyroidism is found among people who take Spironolactone, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Furosemide, and have High blood pressure . We study 29,710 people who have side effects while taking Spironolactone from FDA. Among them, 128 have Hypothyroidism. Find out below who they are, when they have Hypothyroidism and more.

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Spironolactone

Spironolactone has active ingredients of spironolactone. It is often used in acne. (latest outcomes from Spironolactone 43,249 users)

Hypothyroidism

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) has been reported by people with osteoporosis, high blood pressure, hypothyroidism, osteopenia, depression (latest reports from 77,198 Hypothyroidism patients).

On Nov, 19, 2016

29,710 people reported to have side effects when taking Spironolactone.
Among them, 128 people (0.43%) have Hypothyroidism


Number of reports submitted per year:

Could Spironolactone cause Hypothyroidism?

Time on Spironolactone when people have Hypothyroidism *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 55.56 %
  • 6 - 12 months: 11.11 %
  • 1 - 2 years: 22.22 %
  • 2 - 5 years: 11.11 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hypothyroidism when taking Spironolactone *:

  • female: 67.2 %
  • male: 32.8 %

Age of people who have Hypothyroidism when taking Spironolactone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.87 %
  • 40-49: 4.67 %
  • 50-59: 10.28 %
  • 60+: 83.18 %

Top co-used drugs for these people *:

  • Furosemide (46 people, 35.94%)
  • Lasix (38 people, 29.69%)
  • Aspirin (38 people, 29.69%)
  • Digoxin (37 people, 28.91%)
  • Levothyroxine Sodium (34 people, 26.56%)

Forecasts by ePatient.care (We will alert you to new symptoms or undetected conditions when you take Spironolactone, learn more )

Potential co-existing conditions

  • Oedema (10 people, 7.81%)
  • Neoplasm Malignant (9 people, 7.03%)
  • Metastases To Spine (9 people, 7.03%)
  • Calcium Deficiency (9 people, 7.03%)
  • Arrhythmias (9 people, 7.03%)

Potential co-existing symptoms

  • Weakness (36 people, 28.12%)
  • Dizziness (35 people, 27.34%)
  • Atrial Fibrillation/flutter (33 people, 25.78%)
  • High Blood Pressure (30 people, 23.44%)
  • Fatigue (29 people, 22.66%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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