Review: could Spironolactone cause Weight Gain?


Weight gain is found among people who take Spironolactone, especially for people who are female, 60+ old , have been taking the drug for 2 - 5 years, also take medication Furosemide, and have Cardiac disorder . We study 28,938 people who have side effects while taking Spironolactone from FDA and social media. Among them, 706 have Weight gain. Find out below who they are, when they have Weight gain and more.

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Spironolactone has active ingredients of spironolactone. It is often used in high blood pressure. (latest outcomes from Spironolactone 29,598 users)

Weight Gain

Weight gain has been reported by people with breathing difficulty, oedema peripheral, memory loss, fatigue, dizziness (latest reports from 82,979 Weight gain patients).

On Aug, 23, 2016

28,938 people reported to have side effects when taking Spironolactone.
Among them, 706 people (2.44%) have Weight Gain

Number of reports submitted per year:

Could Spironolactone cause Weight gain?

Time on Spironolactone when people have Weight Gain *:

  • < 1 month: 12.2 %
  • 1 - 6 months: 24.39 %
  • 6 - 12 months: 14.63 %
  • 1 - 2 years: 12.2 %
  • 2 - 5 years: 29.27 %
  • 5 - 10 years: 2.44 %
  • 10+ years: 4.88 %

Gender of people who have Weight Gain when taking Spironolactone *:

  • female: 59.51 %
  • male: 40.49 %

Age of people who have Weight Gain when taking Spironolactone *:

  • 0-1: 0.51 %
  • 2-9: 0.84 %
  • 10-19: 1.35 %
  • 20-29: 2.69 %
  • 30-39: 7.07 %
  • 40-49: 25.25 %
  • 50-59: 16.67 %
  • 60+: 45.29 %

Severity if Weight Gain when taking Spironolactone **:

  • least: 9.52 %
  • moderate: 19.05 %
  • severe: 61.9 %
  • most severe: 9.52 %

How people recovered from Weight Gain **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Cardiac Disorder (52 people)
  • Obesity (49 people)
  • Hypertension (45 people)
  • Pulmonary Arterial Hypertension (44 people)
  • Pulmonary Hypertension (33 people)

Top co-used drugs for these people *:

  • Furosemide (263 people)
  • Lasix (191 people)
  • Aspirin (168 people)
  • Digoxin (160 people)
  • Lisinopril (150 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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