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Review: could Spironolactone cause Weight gain?

Summary: Weight gain could be caused by Spironolactone, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take Furosemide, and have Cardiac disorder.

We study 25,278 people who have side effects while taking Spironolactone from FDA and social media. Among them, 624 have Weight gain. Find out below who they are, when they have Weight gain and more.

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Spironolactone

Spironolactone (latest outcomes from 26,338 users) has active ingredients of spironolactone. It is often used in acne.

Weight gain

Weight gain (latest reports from 521,528 patients) has been reported by people with depression, high blood pressure, bipolar disorder, pain, high blood cholesterol.

On Apr, 10, 2014: 25,245 people reported to have side effects when taking Spironolactone. Among them, 624 people (2.47%) have Weight Gain. They amount to 0.12% of all the 520,663 people who have Weight Gain on eHealthMe.

Trend of Weight gain in Spironolactone reports

Time on Spironolactone when people have Weight gain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Weight gain16.67%20.00%13.33%10.00%36.67%3.33%0.00%

Age of people who have Weight gain when taking Spironolactone * :

0-12-910-1920-2930-3940-4950-5960+
Weight gain0.53%0.88%1.05%2.10%6.65%25.57%15.59%47.64%

Severity of Weight gain when taking Spironolactone ** :

leastmoderateseveremost severe
Weight gain7.69%7.69%84.62%0.00%

How people recovered from Weight gain ** :

while on the drugafter off the drugnot yet
Weight gain0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Cardiac disorder (52 people, 8.33%)
  2. Obesity (49 people, 7.85%)
  3. Fluid retention (43 people, 6.89%)
  4. Blood pressure (41 people, 6.57%)
  5. Muscle spasms (36 people, 5.77%)

Top co-used drugs for these people * :

  1. Furosemide (245 people, 39.26%)
  2. Lasix (197 people, 31.57%)
  3. Aspirin (192 people, 30.77%)
  4. Digoxin (156 people, 25.00%)
  5. Lisinopril (149 people, 23.88%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Spironolactone, Weight gain

You can also:

On eHealthMe, Spironolactone (spironolactone) is often used for acne. Find out below the conditions Spironolactone is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Spironolactone used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 months ago):

  • Gained 20 pounds in the past six months

    Reply

Can you answer these questions (what is this?):

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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