Spironolactone and Withdrawal syndrome - from FDA reports


Withdrawal syndrome is found among people who take Spironolactone, especially for people who are female, 50-59 old also take medication Digoxin, and have High blood pressure . We study 41,237 people who have side effects while taking Spironolactone from FDA. Among them, 29 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

What to expect?

If you take Spironolactone and have Withdrawal syndrome, find out what symptoms you could have in 1 year or longer.

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Withdrawal Syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, back pain, muscle spasticity (latest reports from 13,481 Withdrawal syndrome patients).

On Feb, 12, 2017

41,237 people reported to have side effects when taking Spironolactone.
Among them, 29 people (0.07%) have Withdrawal Syndrome

Number of reports submitted per year:

Could Spironolactone cause Withdrawal syndrome?

Gender of people who have Withdrawal Syndrome when taking Spironolactone *:

  • female: 62.96 %
  • male: 37.04 %

Age of people who have Withdrawal Syndrome when taking Spironolactone *:

  • 0-1: 4.76 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 33.33 %
  • 60+: 28.57 %

Top conditions involved for these people *:

  • High Blood Pressure (6 people, 20.69%)
  • Stress And Anxiety (4 people, 13.79%)
  • Pain (3 people, 10.34%)
  • Fibromyalgia (3 people, 10.34%)
  • Restless Leg Syndrome (2 people, 6.90%)

Top co-used drugs for these people *:

  • Digoxin (8 people, 27.59%)
  • Lasix (7 people, 24.14%)
  • Aspirin (6 people, 20.69%)
  • Lisinopril (5 people, 17.24%)
  • Gabapentin (5 people, 17.24%)

Top other side effects for these people *:

  • Tremor (6 people, 20.69%)
  • Dizziness (6 people, 20.69%)
  • Stress And Anxiety (5 people, 17.24%)
  • Emotional Distress (5 people, 17.24%)
  • Nausea (4 people, 13.79%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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