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Review: could Spironolactone cause Withdrawal syndrome?

Summary: Withdrawal syndrome could be caused by Spironolactone, especially for people who are male, 40-49 old, also take Digoxin, and have Hypertension.

We study 25,278 people who have side effects while taking Spironolactone from FDA and social media. Among them, 22 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

On Apr, 15, 2014: 25,278 people reported to have side effects when taking Spironolactone. Among them, 22 people (0.09%) have Withdrawal Syndrome. They amount to 0.04% of all the 55,393 people who have Withdrawal Syndrome on eHealthMe.

Trend of Withdrawal syndrome in Spironolactone reports

Time on Spironolactone when people have Withdrawal syndrome * :

n/a

Age of people who have Withdrawal syndrome when taking Spironolactone * :

0-12-910-1920-2930-3940-4950-5960+
Withdrawal syndrome0.00%0.00%0.00%0.00%0.00%33.33%33.33%33.33%

Severity of Withdrawal syndrome when taking Spironolactone ** :

n/a

How people recovered from Withdrawal syndrome ** :

n/a

Top conditions involved for these people * :

  1. Hypertension (6 people, 27.27%)
  2. Anxiety (4 people, 18.18%)
  3. Fibromyalgia (3 people, 13.64%)
  4. Pain (3 people, 13.64%)
  5. Insomnia (2 people, 9.09%)

Top co-used drugs for these people * :

  1. Digoxin (7 people, 31.82%)
  2. Aspirin (7 people, 31.82%)
  3. Lasix (6 people, 27.27%)
  4. Lisinopril (5 people, 22.73%)
  5. Xanax (4 people, 18.18%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Spironolactone, Withdrawal syndrome

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On eHealthMe, Spironolactone (spironolactone) is often used for acne. Find out below the conditions Spironolactone is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Spironolactone used for and how effective is it:

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Comments from related studies:

  • From this study (1 day ago):

  • My endocrinologist /doctor has my fluid intake limited to 48 ounces of liquids per day (all liquids) because my sodium levels were off due to the drug spironolactone , I was taking 200 mg per day but have cut back to 100 mg per day for the last year.
    Also my Crestor dosage is 20 mg per day.

    Reply

  • From this study (3 weeks ago):

  • I also quit smoking last July and have put on a lot of weight and have not been able to lose it so far. I have also been dealing with a lot of depression and I am in perimenopause. I have been diagnosed with polycystic ovary syndrome by an endrocrine dr. but my obgyn does not agree with that diagnosis and neither do I.

    Reply

  • From this study (4 weeks ago):

  • Had echo gram and told I had pulmionary hypertension moderate to severe could any of these medicines be the cause

    Reply

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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