Spironolactone and Withdrawal syndrome - from FDA reports


Withdrawal syndrome is found among people who take Spironolactone, especially for people who are female, 50-59 old also take medication Lasix, and have Narcolepsy. This review analyzes which people have Withdrawal syndrome with Spironolactone. It is created by eHealthMe based on reports of 47,108 people who have side effects when taking Spironolactone from FDA , and is updated regularly.

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If you take Spironolactone and have Withdrawal syndrome, find out what symptoms you could have in 1 year or longer.

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On Sep, 20, 2017

47,108 people reported to have side effects when taking Spironolactone.
Among them, 36 people (0.08%) have Withdrawal syndrome

Number of reports submitted per year:

Could Spironolactone cause Withdrawal syndrome?

Gender of people who have Withdrawal syndrome when taking Spironolactone *:

  • female: 70.59 %
  • male: 29.41 %

Age of people who have Withdrawal syndrome when taking Spironolactone *:

  • 0-1: 3.85 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 11.54 %
  • 40-49: 26.92 %
  • 50-59: 34.62 %
  • 60+: 23.08 %

Top conditions involved for these people *:

  • Stress And Anxiety (4 people, 11.11%)
  • Narcolepsy (4 people, 11.11%)
  • Pain (3 people, 8.33%)
  • Fibromyalgia (3 people, 8.33%)
  • Cataplexy (3 people, 8.33%)

Top co-used drugs for these people *:

  • Lasix (9 people, 25.00%)
  • Digoxin (8 people, 22.22%)
  • Aspirin (6 people, 16.67%)
  • Synthroid (5 people, 13.89%)
  • Gabapentin (5 people, 13.89%)

Top other side effects for these people *:

  • Dizziness (7 people, 19.44%)
  • Tremor (6 people, 16.67%)
  • Stress And Anxiety (6 people, 16.67%)
  • Confusional State (6 people, 16.67%)
  • Emotional Distress (5 people, 13.89%)

* Approximation only. Some reports may have incomplete information.

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Withdrawal syndrome and Spironolactone from FDA and eHealthMe reports


Spironolactone has active ingredients of spironolactone. It is often used in acne. (latest outcomes from Spironolactone 49,296 users)

Withdrawal syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) has been reported by people with depression, pain, stress and anxiety, fibromyalgia, back pain (latest reports from 16,148 Withdrawal syndrome patients).

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