Review: could Sulfamethoxazole And Trimethoprim cause Clostridium Difficile Colitis?


Clostridium difficile colitis is found among people who take Sulfamethoxazole And Trimethoprim, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Fluconazole, and have Prophylaxis . We study 6,436 people who have side effects while taking Sulfamethoxazole and trimethoprim from FDA and social media. Among them, 27 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.

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Sulfamethoxazole And Trimethoprim

Sulfamethoxazole and trimethoprim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. (latest outcomes from Sulfamethoxazole and trimethoprim 7,114 users)

Clostridium Difficile Colitis

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) has been reported by people with multiple myeloma, high blood pressure, osteoporosis, pain, multiple sclerosis (latest reports from 6,129 Clostridium difficile colitis patients).

On Oct, 21, 2016

6,436 people reported to have side effects when taking Sulfamethoxazole And Trimethoprim.
Among them, 27 people (0.42%) have Clostridium Difficile Colitis

Number of reports submitted per year:

Could Sulfamethoxazole and trimethoprim cause Clostridium difficile colitis?

Time on Sulfamethoxazole And Trimethoprim when people have Clostridium Difficile Colitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Clostridium Difficile Colitis when taking Sulfamethoxazole And Trimethoprim *:

  • female: 54.55 %
  • male: 45.45 %

Age of people who have Clostridium Difficile Colitis when taking Sulfamethoxazole And Trimethoprim *:

  • 0-1: 0.0 %
  • 2-9: 4.17 %
  • 10-19: 8.33 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 29.17 %
  • 50-59: 20.83 %
  • 60+: 37.5 %

Top conditions involved for these people *:

  • Prophylaxis (6 people, 22.22%)
  • Urinary Tract Infection (5 people, 18.52%)
  • Immunosuppression (3 people, 11.11%)
  • Hypertension (3 people, 11.11%)
  • Gastrooesophageal Reflux Disease (3 people, 11.11%)

Top co-used drugs for these people *:

  • Mycophenolate Mofetil (8 people, 29.63%)
  • Fluconazole (8 people, 29.63%)
  • Everolimus (6 people, 22.22%)
  • Cefepime (6 people, 22.22%)
  • Methylprednisolone (5 people, 18.52%)

Top other side effects for these people *:

  • Headache (7 people, 25.93%)
  • Hypertension (6 people, 22.22%)
  • Transplant Rejection (5 people, 18.52%)
  • Hypotension (5 people, 18.52%)
  • Nephropathy Toxic (4 people, 14.81%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim?

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