Review: could Sulfamethoxazole and trimethoprim cause Clostridium difficile colitis?
Summary: Clostridium difficile colitis is found among people who take Sulfamethoxazole and trimethoprim, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Fluconazole, and have Urinary tract infection.
We study 5,543 people who have side effects while taking Sulfamethoxazole and trimethoprim from FDA and social media. Among them, 22 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.
You are not alone: join a mobile support group for people who take Sulfamethoxazole and trimethoprim and have Clostridium difficile colitis >>>
Sulfamethoxazole and trimethoprim
Sulfamethoxazole and trimethoprim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. (latest outcomes from 5,756 Sulfamethoxazole and trimethoprim users)
Clostridium difficile colitis
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) has been reported by people with high blood pressure, osteoporosis, multiple myeloma, pain, multiple sclerosis. (latest reports from 3,639 Clostridium difficile colitis patients)
On Feb, 3, 2015: 5,542 people reported to have side effects when taking Sulfamethoxazole and trimethoprim. Among them, 22 people (0.40%) have Clostridium Difficile Colitis.
Time on Sulfamethoxazole and trimethoprim when people have Clostridium difficile colitis * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years |
|Clostridium difficile colitis||100.00%||0.00%||0.00%||0.00%||0.00%||0.00%||0.00% |
Gender of people who have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim * :
|Clostridium difficile colitis||55.00%||45.00% |
Age of people who have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim * :
|Clostridium difficile colitis||0.00%||0.00%||9.09%||0.00%||0.00%||27.27%||27.27%||36.36% |
Severity of Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim ** :
How people recovered from Clostridium difficile colitis ** :
Top conditions involved for these people * :
- Urinary tract infection (5 people, 22.73%)
- Prophylaxis (4 people, 18.18%)
- Pneumocystis jiroveci pneumonia (2 people, 9.09%)
- Chronic graft versus host disease (2 people, 9.09%)
- Glomerulonephritis rapidly progressive (2 people, 9.09%)
Top co-used drugs for these people * :
- Fluconazole (9 people, 40.91%)
- Mycophenolate mofetil (8 people, 36.36%)
- Prednisone (6 people, 27.27%)
- Methylprednisolone (5 people, 22.73%)
- Ciprofloxacin (5 people, 22.73%)
* Approximation only. Some reports may have incomplete information.
** Reports from social media are used.
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Do you have Clostridium Difficile Colitis while taking Sulfamethoxazole And Trimethoprim?
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Drugs in real world that are associated with:
Could your condition cause:
Can you answer these questions (Ask a question):
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- Can a cortisone shot cause c-diff
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- Can bactrim ds treat shingle?
I am wondering can Bactrim DS treat shingles? Because l am HIV POSITIVE my specialist prescribed me Bactrim DS and Atripla, and l realise Bactrim DS is an antiviral tablets that is why l like to know whether l can use Bactrim DS to treat shingles. This is the second times l have shingles. Please help me!
- Can sulfamethoxazole-tmp ds, raise or lower blood sugar. (1 answer)
Symptoms the last 10 days are chills, sweating, light fever (98.9 to 100) sometimes. General malaise, tired, poor sleep. Just depressed, because of the recurrent Infection that no antibiotics (supposedly the bacteria Klesiella-pneumoniae is Sensitive to all the antibiotics I have taken so far)has cleared this stuborn condition.
- How long did the hives/itching eyes last?
had back to back allergic reactions to iv abx - after clinda (april 2014) developed sjs - still having hives around my eyes, watering, and severe itching. have been on 4x dose zyrtec, prn benadryl. when will this go away?
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- Cdifficile treatment
I had drug (cipro) induced cdifficile for three and a half years and was hospitalized 3 times and went through absolute hell until my Dr. finally agreed to do a fecal transplant. Even then the first transfer done via a lower bowel infusion didnt work. Two weeks after the first one he did a full colonoscopy transfer going up as high as my appendix and that one worked immediatly and I have had no furthur bowel problems, no diarrea at all and its' now been well over a year. I took every type of cdiff drug imaginable prior to that. I had to stay on Vancomyicin all the time or I would be spending all my time going back and forth to the john 20 or 30 times a day. I was so ill that I could bearly keep my head up. I couldnt eat without an urgent bathroom trip. I had to wear Depends all the time, my skin was raw and sore from constant wiping. I was given Tinture of Morphine to slow me down. That helped some. My veins collapsed from all the test shots and from the many pints of saline to keep me hydrated. My heart stopped from a lowering of my potassium level and I had to get a pacemaker to control my heart rate. I spent a fortune on the drugs,some costing as much as $1200.00 a month, more than I make working and working was rough. I would have to go to the restroom so often and I work outside where there were frequently no facilities. I would have to bring a complete change of clothes and a disinfecting kit with me to cleanup the restroom. I washed my hands raw. You cant leave that for someone else or they might get sick too as it is highly infectious. Hospitals are not that meticulous either. I once had to go to a Long Island Hospital that failed the precautions test miserably. They assigned me to a room with another patient whose family wanted to eat their meals in our shared room and then use the bathroom. I pitched a fit on them and told them no way were they going to eat in that room or use the bathroom. I can't imagine what that hospital was thinking. Anyway you get the idea....3 years of expensive treatment and all I needed was some healthy donor poop and someone willing to mix it up in a blender and put it in syringe and put it up the wassoo and I was done. Dont let them give you all the expensive treatment if you have a resistant case of cdiff, insist on the fecal transplant right off, you will be very glad you did. The donor should be someone in your family, preferably someone young with lots of good flora for digestion. Someone without other gut problems...they need to test them too. Bring it in the afternoon before and Bingo,you will be back on track the next day. I am open to answer questions or be tested orhelp with anything else you might want to know, just ask me.
- Bactrim causes severe side effects (1 response)
I get bladder infections on a regular basis. I do not have a doctor so I end up in the ER every time. I normally go to the same ER but not all the time. I have been prescribed medications like Cipro and Bactrim. Cipro usually knocks out the infection but I always get another one.
For the last three years Doctors have been prescribing me Bactrim. In the last two months I had three bladder infections and took Bactrim for ten days seven and three. I didn't realize the medications themselves would harm me as well. Now I have severe abdominal pain every single day. I did some research on Bactrim and discovered it can cause several different kinds of stomach problems. I have been in pain for two months straight non-stop.
I finally discovered that the Bactrim killed both the good and bad bacteria in my body and now my digestive system is off balance. I went to a natural food store and bought some probiotics. It helped relieve some stomach pain after four days, but if I forget to take it one time it comes back. I think something is wrong with me but not exactly sure what. When I get a doctor next month I will update this article.
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Comments from related studies:
From this study (5 days ago):
I have had C-diff since 9/3 2014. I am on my 5th reoccurrence of it, and I took flagyl twice and vancomyacin with the secondary medication. no relief. Ended in the hospital with dehydration, lack of potassium and felt horrible.
My moods, have been up and down, since I just came down with a bladder infection two weeks before my fecal transplant and it took them a week to give me the antibiotics. They gave me bacteria, and all of the sudden on the 4th day my knees hurt, my upper thighs. I do wonder what is wrong. I have always been a very compliant do not complain patient but gosh, I feel like I am going to die from .
I do not know how I can continue to work?
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