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Review: could Sulfamethoxazole and trimethoprim cause Clostridium difficile colitis?

We study 5,529 people who have side effects while taking Sulfamethoxazole and trimethoprim from FDA and social media. Among them, 22 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.

Stay connected: join a mobile support group for people who take Sulfamethoxazole and trimethoprim and have Clostridium difficile colitis >>>

Sulfamethoxazole and trimethoprim

Sulfamethoxazole and trimethoprim (latest outcomes from 5,740 users) has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection.

Clostridium difficile colitis

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) (latest reports from 31,194 patients) has been reported by people with high blood pressure, osteoporosis, multiple myeloma, pain, multiple sclerosis.

On Aug, 14, 2014: 5,529 people reported to have side effects when taking Sulfamethoxazole and trimethoprim. Among them, 22 people (0.40%) have Clostridium Difficile Colitis. They amount to 0.07% of all the 31,188 people who have Clostridium Difficile Colitis on eHealthMe.

Trend of Clostridium difficile colitis in Sulfamethoxazole and trimethoprim reports

Time on Sulfamethoxazole and trimethoprim when people have Clostridium difficile colitis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Clostridium difficile colitis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim * :

FemaleMale
Clostridium difficile colitis55.00%45.00%

Age of people who have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim * :

0-12-910-1920-2930-3940-4950-5960+
Clostridium difficile colitis0.00%0.00%9.09%0.00%0.00%27.27%27.27%36.36%

Severity of Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim ** :

n/a

How people recovered from Clostridium difficile colitis ** :

n/a

Top conditions involved for these people * :

  1. Urinary tract infection (5 people, 22.73%)
  2. Prophylaxis (4 people, 18.18%)
  3. Pneumocystis jiroveci pneumonia (2 people, 9.09%)
  4. Chronic graft versus host disease (2 people, 9.09%)
  5. Glomerulonephritis rapidly progressive (2 people, 9.09%)

Top co-used drugs for these people * :

  1. Fluconazole (9 people, 40.91%)
  2. Mycophenolate mofetil (8 people, 36.36%)
  3. Prednisone (6 people, 27.27%)
  4. Methylprednisolone (5 people, 22.73%)
  5. Ciprofloxacin (5 people, 22.73%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Sulfamethoxazole and trimethoprim and have Clostridium Difficile Colitis
- group for people who take Sulfamethoxazole and trimethoprim
- group for people who have Clostridium Difficile Colitis

Comments from related studies:

  • From this study (6 days ago):

  • left bicep and thumb weakness after 3 days on antibiotic combo. Slightly elevated AST and ALT levels.

    Reply

  • From this study (2 weeks ago):

  • Also have Bartonella. Probably having a herxheimer reaction.

    Dysphalgia has been intermittent and infrequent, but episodes last for several days.

    Begins suddenly, rather than getting progressively worse.

    Can swallow liquids (including thick ones like milkshakes) without trouble, but solids take concentrated effort and cause pain. Have pain in one ear, and swallowing solids increases it along with giving me pain on the right side of my throat.

    Reply

    Mart100 on Jul, 17, 2014:

    Male
    23

    Hi, just come over this comment whilst searching similar symptoms I have had. Been feeling under the weather for a while now, symptoms that match lymphoma/bartonella, blood tests and xray have come back fine, any suggestion?

    Reply

  • From this study (4 weeks ago):

  • Started from genitals and broke into plac across my whole body

    Reply

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On eHealthMe, Sulfamethoxazole And Trimethoprim (sulfamethoxazole; trimethoprim) is often used for urinary tract infection. Find out below the conditions Sulfamethoxazole And Trimethoprim is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

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