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Review: could Sulfamethoxazole and trimethoprim cause Clostridium difficile colitis?





Summary: Clostridium difficile colitis is found among people who take Sulfamethoxazole and trimethoprim, especially for people who are female, 60+ old, have been taking the drug for < 1 month, also take medication Fluconazole, and have Urinary tract infection.

We study 5,538 people who have side effects while taking Sulfamethoxazole and trimethoprim from FDA and social media. Among them, 22 have Clostridium difficile colitis. Find out below who they are, when they have Clostridium difficile colitis and more.

You are not alone: join a mobile support group for people who take Sulfamethoxazole and trimethoprim and have Clostridium difficile colitis >>>

Sulfamethoxazole and trimethoprim

Sulfamethoxazole and trimethoprim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. (latest outcomes from Sulfamethoxazole and trimethoprim 5,752 users)

Clostridium difficile colitis

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) has been reported by people with high blood pressure, osteoporosis, multiple myeloma, pain, multiple sclerosis.(latest reports from Clostridium difficile colitis 3,626 patients)

On Nov, 28, 2014: 5,534 people reported to have side effects when taking Sulfamethoxazole and trimethoprim. Among them, 22 people (0.40%) have Clostridium Difficile Colitis.

Trend of Clostridium difficile colitis in Sulfamethoxazole and trimethoprim reports

Time on Sulfamethoxazole and trimethoprim when people have Clostridium difficile colitis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Clostridium difficile colitis100.00%0.00%0.00%0.00%0.00%0.00%0.00%

Gender of people who have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim * :

FemaleMale
Clostridium difficile colitis55.00%45.00%

Age of people who have Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim * :

0-12-910-1920-2930-3940-4950-5960+
Clostridium difficile colitis0.00%0.00%9.09%0.00%0.00%27.27%27.27%36.36%

Severity of Clostridium difficile colitis when taking Sulfamethoxazole and trimethoprim ** :

n/a

How people recovered from Clostridium difficile colitis ** :

n/a

Top conditions involved for these people * :

  1. Urinary tract infection (5 people, 22.73%)
  2. Prophylaxis (4 people, 18.18%)
  3. Pneumocystis jiroveci pneumonia (2 people, 9.09%)
  4. Chronic graft versus host disease (2 people, 9.09%)
  5. Glomerulonephritis rapidly progressive (2 people, 9.09%)

Top co-used drugs for these people * :

  1. Fluconazole (9 people, 40.91%)
  2. Mycophenolate mofetil (8 people, 36.36%)
  3. Prednisone (6 people, 27.27%)
  4. Methylprednisolone (5 people, 22.73%)
  5. Ciprofloxacin (5 people, 22.73%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Clostridium Difficile Colitis while taking Sulfamethoxazole And Trimethoprim?

You are not alone! Join a mobile support group:
- support group for people who take Sulfamethoxazole and trimethoprim and have Clostridium Difficile Colitis
- support group for people who take Sulfamethoxazole and trimethoprim
- support group for people who have Clostridium Difficile Colitis

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More questions for: Sulfamethoxazole and trimethoprim, Clostridium difficile colitis

You may be interested at these reviews (Write a review):

  • Bactrim causes severe side effects (1 response)
    I get bladder infections on a regular basis. I do not have a doctor so I end up in the ER every time. I normally go to the same ER but not all the time. I have been prescribed medications like Cipro and Bactrim. Cipro usually knocks out the infection but I always get another one.
    For the last three years Doctors have been prescribing me Bactrim. In the last two months I had three bladder infections and took Bactrim for ten days seven and three. I didn't realize the medications themselves would harm me as well. Now I have severe abdominal pain every single day. I did some research on Bactrim and discovered it can cause several different kinds of stomach problems. I have been in pain for two months straight non-stop.
    I finally discovered that the Bactrim killed both the good and bad bacteria in my body and now my digestive system is off balance. I went to a natural food store and bought some probiotics. It helped relieve some stomach pain after four days, but if I forget to take it one time it comes back. I think something is wrong with me but not exactly sure what. When I get a doctor next month I will update this article.
    I just want to say that Bactrim has severe side effects, I DO NOT recommend taking this drug. Cipro is better in the long run.
    Reply
  • Something should be done....
    Medicine had my kness aching badly. Cause my legs to lock up where I couldn't bend then. Had to elevate for 2weeks. Feeling better but they still hurt and knees keep popping. Had to take fluid pills cause they were so swollen.
    Reply
  • Interaction between bactrim & vit c
    I drank one tablet of bactrim with glass of vit C (1 tablet), after 5 minutes I became red (face & eyes) with high tachycardia and high pressure in the ears.

    After 15 minutes I observed differents red points on the skin (hand, arms & legs).



    I would like to inform you that I took in the past bactrim and vit C but separately, never both in the same moment.

    I was afraid to have an internal emoragy, I provoked the vomiting to eliminate everything in my stomach.

    Affer 10 minutes the situation became normal and pressure returned normal.



    I took 1 tablet of antistaminc for allergy and the red points eliminated.
    Reply
  • Clindamycin induced clostridium difficile colitis (1 response)
    Dentist prescribed 10 day prescription of Clindamycin for tooth ache, where a week after completing it, a near fatal CDiff infection developed. Renal failure and 3 weeks in hospital followed by 2 months of rehab. No probiotics were taken with the antibiotic. Vancomycin and Flagyl cured the CDiff infection.



    Advice: DO NOT TAKE THIS DRUG, IT IS TOO DESTRUCTIVE!
    Reply

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