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Review: could Sulfasalazine cause Anterior uveitis (Uveitis)?

Summary: Anterior uveitis is found among people who take Sulfasalazine, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years, also take medication Methotrexate, and have Rheumatoid arthritis.

We study 11,413 people who have side effects while taking Sulfasalazine from FDA and social media. Among them, 20 have Anterior uveitis. Find out below who they are, when they have Anterior uveitis and more.

You are not alone: join a mobile support group for people who take Sulfasalazine and have Anterior uveitis >>>


Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. (latest outcomes from Sulfasalazine 11,744 users)

Anterior uveitis

Anterior uveitis (inflammation of the middle layer of the eye, which includes the iris (coloured part of the eye) and adjacent tissue, known as the ciliary body) has been reported by people with ankylosing spondylitis, rheumatoid arthritis, macular degeneration, osteoporosis, multiple sclerosis.(latest reports from Anterior uveitis 4,596 patients)

On Dec, 5, 2014: 11,413 people reported to have side effects when taking Sulfasalazine. Among them, 20 people (0.18%) have Anterior Uveitis.

Trend of Anterior uveitis in Sulfasalazine reports

Time on Sulfasalazine when people have Anterior uveitis * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Anterior uveitis0.00%0.00%0.00%100.00%0.00%0.00%0.00%

Gender of people who have Anterior uveitis when taking Sulfasalazine * :

Anterior uveitis66.67%33.33%

Age of people who have Anterior uveitis when taking Sulfasalazine * :

Anterior uveitis0.00%0.00%0.00%12.50%0.00%62.50%6.25%18.75%

Severity of Anterior uveitis when taking Sulfasalazine ** :

leastmoderateseveremost severe
Anterior uveitis0.00%100.00%0.00%0.00%

How people recovered from Anterior uveitis ** :

while on the drugafter off the drugnot yet
Anterior uveitis0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis (10 people, 50.00%)
  2. Ankylosing spondylitis (4 people, 20.00%)
  3. Chronic myeloid leukaemia (1 people, 5.00%)
  4. Arthritis (1 people, 5.00%)
  5. Anaemia (1 people, 5.00%)

Top co-used drugs for these people * :

  1. Methotrexate (9 people, 45.00%)
  2. Humira (8 people, 40.00%)
  3. Enbrel (8 people, 40.00%)
  4. Folic acid (5 people, 25.00%)
  5. Arava (5 people, 25.00%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Anterior Uveitis while taking Sulfasalazine?

You are not alone! Join a mobile support group:
- support group for people who take Sulfasalazine and have Anterior Uveitis
- support group for people who take Sulfasalazine
- support group for people who have Anterior Uveitis

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • What side effects do you experience from sulpfasalazine? (3 answers)
    (Asked by a 58 year old woman who has Rheumatoid Arthritis, and takes Sulfasalazine)
    I began taking sulfasalazine 5 days ago for Rheumatoid arthritis. Since then I've had stomach cramps and bloating. Has anyone else experienced these side effects? If so, did the symptoms go away after using taking the meds for a while? And did the meds help the RA symptoms?
  • Which drug seems more effective for ra pain?
    (Asked by a 56 year old woman who has Fibromyalgia, Rheumatoid Arthritis, Osteoarthritis, and takes Sulfasalazine, Celebrex, Cymbalta)
    Severe RA - taking sulfasalazine, but extreme fatigue. Good pain relief with celebrax and cymbalta. Taking prednisone for 6 months, tapering to half a tablet for one month. My concerns are swollen eyelids and hair loss. Anyone know if swelling, especially bad when waking in morning is typical for my ...
  • Does sulfasalazine make you gain weight (3 answers)
    (Asked by a 51 year old woman who has Arthritis - Rheumatoid, and takes Sulfasalazine)
    I have steadily gained weight while on this drug has anybody had the same weight gain I do not eat much at all and average activeness nothing different in this since starting the tablets very confused.
  • What systemic treatments work for uveitis?
    (Asked by a 57 year old woman who has Uveitis, and takes Methotrexate)
    I am taking methotrexate injections for uveitis and not having much luck controlling it. The side effects are horrible. I am bedridden for several days. If I am very lucky I have 1, mayby 2 good days a week then it is time for the next injection.
  • The last 3 years i have been experiences excessive sweating when doing minor things. this is new for me. i have a history of crohn's disease and have developed arthritis the last 4 years.
    (Asked by a 62 year old man who has Arhtritis, Crohn's Disease, Sweating - Excessive, and takes Pramipexole Dihydrochloride, Sulfasalazine, Effexor, Atenolol, Folic Acid, Diphenoxylate Hydrochloride W/ Atropine Sulfate, Methotrexate, Omeprazole, Celebrex)
    I have dealt with Crohn's disease for 40 years. I've had several bowel resections, and live with diarrhea. Within the last 5 years I developed severe arthritis in my feet. The doctors felt everything is auto-immune related. I had the bone in both feet fused to lessen the pain. For the past 4 years I ...

More questions for: Sulfasalazine, Anterior uveitis

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  • Sulfasalazine and the never ending menstrual cycle
    (Posted by a 43 year old woman who has Arthritis - Rheumatoid, and takes Sulfasalazine)
    I started this drug and never had menstrual problems begore. Within 3 months, I started my period and it never stopped even with stopping the drug for 3 mon ths. I ended up going my gyne and he prescribed megace. I had been bleeding for a total of 6 months. Made an appt with my rhuemy and explai ...

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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