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Review: could Tizanidine cause Depression?

Summary: Depression could be caused by Tizanidine, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months, also take Gabapentin, and have Multiple sclerosis.

We study 1,164 people who have side effects while taking Tizanidine from FDA and social media. Among them, 46 have Depression. Find out below who they are, when they have Depression and more.

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On Apr, 14, 2014: 1,164 people reported to have side effects when taking Tizanidine hydrochloride. Among them, 46 people (3.95%) have Depression. They amount to 0.00% of all the 1,146,471 people who have Depression on eHealthMe.

Trend of Depression in Tizanidine hydrochloride reports

Time on Tizanidine hydrochloride when people have Depression * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Depression0.00%40.00%0.00%20.00%20.00%20.00%0.00%

Gender of people who have Depression when taking Tizanidine hydrochloride * :

FemaleMale
Depression59.09%40.91%

Age of people who have Depression when taking Tizanidine hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Depression0.00%0.00%0.00%10.53%5.26%18.42%63.16%2.63%

Severity of Depression when taking Tizanidine hydrochloride ** :

leastmoderateseveremost severe
Depression0.00%100.00%0.00%0.00%

How people recovered from Depression ** :

while on the drugafter off the drugnot yet
Depression0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Multiple sclerosis (8 people, 17.39%)
  2. Muscle spasms (6 people, 13.04%)
  3. Multiple myeloma (5 people, 10.87%)
  4. Depression (5 people, 10.87%)
  5. Migraine (4 people, 8.70%)

Top co-used drugs for these people * :

  1. Gabapentin (13 people, 28.26%)
  2. Atenolol (9 people, 19.57%)
  3. Zofran (9 people, 19.57%)
  4. Lisinopril (9 people, 19.57%)
  5. Fentanyl (8 people, 17.39%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Tizanidine hydrochloride, Depression

You can also:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used for muscle spasms. Find out below the conditions Tizanidine Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Tizanidine Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (3 months ago):

  • I suffer from severe to moderate memory loss a friend told me it was due to klonopin It has been 7 years though since I suffered a concussion in a car accident. Been trying to get disability forever. I can't even handle a minimum wage job bc the steps I have to take r instantly out of my brain. I have a masters degree. So I don't think it's the concussion I think it's the meds. The muscle relaxant r brand new so we can't blame them. So could it be the klonopin

    Reply

  • From this study (5 months ago):

  • I have several bulging discs in neck from c4 through c7.Spinal stenosis, pinched nerves.I also have had numbness and tingling down right arm,although the discs/nerves are problematic on both sides of the neck.
    I also have spasms in calves and toes that I haven"t told the doctor about yet.

    Reply

  • From this study (4 years ago):

  • After taking Zanaflex for a month on a regualar schedule, drinking regularly I had an episode where I went to sleep and began having nightmares when I openned my eyes they continued and became hallucinations. I could not get up because I was so weak and my head and legs felt so tingly. When I got a up my head was spinning terribley and I was afraid I would faint. This continued the entire day when I would lay down and feel somewhat ok but when I got up my legs and head would tingle and spin. I am still feeling the affects and depression 2 days later.

    Reply

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