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Review: could Tizanidine cause Withdrawal syndrome?

Summary: Withdrawal syndrome could be caused by Tizanidine, especially for people who are female, 50-59 old, also take Fentanyl-100, and have Arthritis.

We study 1,164 people who have side effects while taking Tizanidine from FDA and social media. Among them, 9 have Withdrawal syndrome. Find out below who they are, when they have Withdrawal syndrome and more.

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Tizanidine hydrochloride

Tizanidine hydrochloride (latest outcomes from 1,495 users) has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms.

Withdrawal syndrome

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) (latest reports from 55,438 patients) has been reported by people with depression, pain, acupuncture and pain, stress and anxiety, muscle spasticity.

On Apr, 3, 2014: 1,144 people reported to have side effects when taking Tizanidine hydrochloride. Among them, 9 people (0.79%) have Withdrawal Syndrome. They amount to 0.02% of all the 54,832 people who have Withdrawal Syndrome on eHealthMe.

Trend of Withdrawal syndrome in Tizanidine hydrochloride reports

Time on Tizanidine hydrochloride when people have Withdrawal syndrome * :

n/a

Gender of people who have Withdrawal syndrome when taking Tizanidine hydrochloride * :

FemaleMale
Withdrawal syndrome54.55%45.45%

Age of people who have Withdrawal syndrome when taking Tizanidine hydrochloride * :

0-12-910-1920-2930-3940-4950-5960+
Withdrawal syndrome0.00%0.00%0.00%0.00%0.00%33.33%66.67%0.00%

Severity of Withdrawal syndrome when taking Tizanidine hydrochloride ** :

n/a

How people recovered from Withdrawal syndrome ** :

n/a

Top conditions involved for these people * :

  1. Arthritis (3 people, 33.33%)
  2. Back pain (3 people, 33.33%)
  3. Muscle spasms (3 people, 33.33%)
  4. Periarthritis (3 people, 33.33%)
  5. Hypertension (2 people, 22.22%)

Top co-used drugs for these people * :

  1. Fentanyl-100 (3 people, 33.33%)
  2. Celebrex (3 people, 33.33%)
  3. Zolpidem (3 people, 33.33%)
  4. Methadone hcl (3 people, 33.33%)
  5. Miacalcin (2 people, 22.22%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Tizanidine hydrochloride, Withdrawal syndrome

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On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used for muscle spasms. Find out below the conditions Tizanidine Hydrochloride is used for, how effective it is, and any alternative drugs that you can use to treat those same conditions.

What is Tizanidine Hydrochloride used for and how effective is it:

Other drugs that are used to treat the same conditions:

Could it be a symptom from a condition:

Drugs in real world that are associated with:

Could your condition cause it?

Comments from related studies:

  • From this study (10 hours ago):

  • Recently Dxd w/ toxic multinodular goiter/hyperthyroidism. Fibromyalgia for 20+ years. Had to titrate off Savella 100 mg. BID due to hyperthyroidism. Now all above symptoms have worsened. Because thyroid blood work was in normal range ( although I had been on low iodine diet for 2 months, which should keep in normal range) endocrinologist said see me in six months! No instructions, no explanations. Can't find much about Plummer's online! Had bad reaction during uptake scan & ER said due to RAI. If levels had been high on blood work following scan results, Dr wanted to do RAI Ablation. I am a.) Afraid of worse reaction; b.) Ablation not working, having to be repeated; c.) Ultimately having to have thyroid removed surgically.
    I need to know my options! What should I be doing now? Anger and aggression, plus crying all the time are taking over my life. Savella was like a miracle drug for my fibromyalgia, but since it was an SNRI I am wondering how much of my problems is from stopping that. I did titrate off professionally, but had been on it over 3 years. Also wondering if it, hyperthyroidism or both are reason I am on four bp meds as cardiologist says heart is healthy. No history of stroke or seizures.
    Is there anyone out there who can give me direction? Every day is worse. Also having injections in c- spine to determine if neurological surgery w/ help w/ spinal cord compression. First was done Monday.
    Eyes also not focusing! Fibromyalgia or hyperthyroidism? Dr says I have 20/20 in each eye individually & field vision test okay. Still can't see TV or anything up close such as cosmetic needs for face! Nothing helps close vision. Glasses will help distance clear enough for now.

    Reply

  • From this study (7 days ago):

  • 5/325 every 4 hours as needed. 0-4 per day. Would like to stop taking this drug as my eye pressure has increased. Only take it if the pain is 10+++. Looking for Orthopedic Surgeon to fix the bulging disks.

    Reply

  • From this study (1 week ago):

  • 1st 3 symptoms due to a tooth extraction on 10/22/12 by an over-zealous dentist. After much effort the tooth finally came out and he exclaimed, "Most dentists would have sent a patient with a tooth like that to an oral surgeon, but I seem to have very good luck in getting them out." Little did I know that he had broken my maxillary bone and a week later I almost died from multiple bacterial infections in my sinus cavity. The bacteria damaged all 3 branches of my Trigeminal nerve and 3 surgeries later I have seen no improvement. Now have double vision in right eye and trigeminal pain 24/7. Gabapentin was a life saver, but only decreases pain and never eliminates it. Severe coughing started soon after starting gabapentin and cough is very wet, as if I have bronchitis. Chest x-Ray 4/7/14 shows normal and my doctor is perplexed. Neurologist has me taking Dextromorphan Hydrobromide, but seems to be ineffective. Help!

    Reply

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- Tizanidine Hydrochloride side effects

 

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