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Review: could Topamax cause Chest pain?

Summary: Chest pain is found among people who take Topamax, especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months, also take medication Seroquel, and have Migraine.

We study 22,606 people who have side effects while taking Topamax from FDA and social media. Among them, 786 have Chest pain. Find out below who they are, when they have Chest pain and more.

You are not alone: join a support group for people who take Topamax and have Chest pain >>>



Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from 24,636 Topamax users)

Chest pain

Chest pain has been reported by people with high blood pressure, osteoporosis, pain, multiple sclerosis, rheumatoid arthritis. (latest reports from 136,852 Chest pain patients)

On Mar, 31, 2015: 22,595 people reported to have side effects when taking Topamax. Among them, 786 people (3.48%) have Chest Pain.

Trend of Chest pain in Topamax reports

Time on Topamax when people have Chest pain * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Chest pain12.16%36.49%10.81%13.51%12.16%12.16%2.70%

Gender of people who have Chest pain when taking Topamax * :

Chest pain83.97%16.03%

Age of people who have Chest pain when taking Topamax * :

Chest pain0.00%0.12%2.38%10.12%18.88%32.50%25.62%10.38%

Severity of Chest pain when taking Topamax ** :

leastmoderateseveremost severe
Chest pain0.00%68.75%31.25%0.00%

How people recovered from Chest pain ** :

while on the drugafter off the drugnot yet
Chest pain0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Migraine (163 people, 20.74%)
  2. Depression (119 people, 15.14%)
  3. Pain (102 people, 12.98%)
  4. Multiple sclerosis (78 people, 9.92%)
  5. Headache (67 people, 8.52%)

Top co-used drugs for these people * :

  1. Seroquel (147 people, 18.70%)
  2. Neurontin (142 people, 18.07%)
  3. Aspirin (119 people, 15.14%)
  4. Zoloft (103 people, 13.10%)
  5. Ambien (102 people, 12.98%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of topamax and chest pain on

Do you have Chest Pain while taking Topamax?




You are not alone! Join a support group on :
- support group for people who take Topamax and have Chest Pain
- support group for people who take Topamax
- support group for people who have Chest Pain

Drugs in real world that are associated with:

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Recent Topamax related drug comparison:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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