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Review: could Topamax cause Fatigue?





Summary: Fatigue is found among people who take Topamax, especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months, also take medication Aspirin, and have Migraine.

We study 22,552 people who have side effects while taking Topamax from FDA and social media. Among them, 1,304 have Fatigue. Find out below who they are, when they have Fatigue and more.

You are not alone: join a mobile support group for people who take Topamax and have Fatigue >>>

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,579 users)

Fatigue

Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.(latest reports from Fatigue 198,350 patients)

On Nov, 25, 2014: 22,540 people reported to have side effects when taking Topamax. Among them, 1,307 people (5.80%) have Fatigue.

Trend of Fatigue in Topamax reports

Time on Topamax when people have Fatigue * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Fatigue25.73%28.16%9.22%10.19%18.93%4.37%3.40%

Gender of people who have Fatigue when taking Topamax * :

FemaleMale
Fatigue80.87%19.13%

Age of people who have Fatigue when taking Topamax * :

0-12-910-1920-2930-3940-4950-5960+
Fatigue0.61%2.89%3.11%10.40%17.08%30.90%26.04%8.96%

Severity of Fatigue when taking Topamax ** :

leastmoderateseveremost severe
Fatigue3.95%39.47%36.84%19.74%

How people recovered from Fatigue ** :

while on the drugafter off the drugnot yet
Fatigue3.23%12.90%83.87%

Top conditions involved for these people * :

  1. Migraine (243 people, 18.59%)
  2. Depression (194 people, 14.84%)
  3. Epilepsy (155 people, 11.86%)
  4. Multiple sclerosis (153 people, 11.71%)
  5. Convulsion (144 people, 11.02%)

Top co-used drugs for these people * :

  1. Aspirin (170 people, 13.01%)
  2. Synthroid (152 people, 11.63%)
  3. Cymbalta (145 people, 11.09%)
  4. Seroquel (142 people, 10.86%)
  5. Xanax (131 people, 10.02%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Fatigue while taking Topamax?

You are not alone! Join a mobile support group:
- support group for people who take Topamax and have Fatigue
- support group for people who take Topamax
- support group for people who have Fatigue

Drugs in real world that are associated with:

Could your condition cause:

Can you answer these questions (Ask a question):

  • What is the time space for taking l-thyroxine and pantoprazole am dose
    also taking Panioprazole in am forty-five minutes before breakfast,
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  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
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  • Can mrsa cause chronic intestinal pseudo obstruction?
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
    I never really recovered... The obstruction returned after 2 days and a portion of necrotic bowel was removed, then further fever and cellulitis then MRSA and deaths door.... Isolation in high dependency (intensive care) wound break down, ventilated and all related issues that come with that - chest infection, pneumonia, bed sores. Total time in hospital 8 months. Negative pressure dressing on laparotomy wound, colostomy, picc, 4 rounds of vancomycin, minor flirt with heart failure (just water related) an eventually everything healed. Had a large incisional hernia to repair and some corrective work to the horrific scarring but then the neuropathy started plus problems eating, spewing up after any solid food, more than a few forks, diarrhoea and sickness or constipation nausea and pain driving me mad, tried all manner of drugs, nerve blocks, physio, floating tank, acupuncture, opiates, non opiates, spinal cord stimulation, an now a consultant just had a 'eureka' moment and said were you treated with vancomycin when you had MRSA? If so I'm pretty sure you have chronic intestinal pseudo obstruction and is 90% sure but wants to take a muscle biopsy to be certain. I've had so much surgery and bad news in the last 10yrs I'm terrified of germs, hospital acquired bugs and anaesthetics, is there any other way? Or can I have this test done awake - conscious sedation? I had it before during spinal cord surgery so I know what's involved and it's better than GA as I know what's going on, who is doing what to me etc...
    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
    Reply
  • What's the best home remedy for jaundice?
    I started out thinking that I had pancreatitis, had all the symptoms, abdominal pain that went all the way thru to the back & inability to digest food (chronic indigestion). I read about keeping the bodys pH better balanced, bought pH test strips (urine) & found I was very acidic. I began eating more alkaline foods, alkalizing my water, and avoiding really acidic foods. Stopped taking my acid reducers because they actually KEPT me more acidic. I noticed that when my body's pH was up (alkaline) the pain was tolerable but when it began to drop (acid) the pain kicked up again. My doctors say they don't necessarily think it's pancreatitis because the ultrasound doesn't show inflammation & my blood test numbers are only slightly elevated. My liver enzymes are also slightly elevated. The doctors don't Seem very concerned. Today, for the first time in 2 months since this whole thing started I noticed I'm jaundiced. What the heck is this?
    Reply
  • Do the side effects of prolia either stop or lessen over the 6 month period between injections?
    I am wondering if the side effects of Prolia go away or lessen during the six months it is taken for.
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More questions for: Topamax, Fatigue

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    am only taking 50mg and have only been taking it for 4 days(this is the evening of the 4th day)as a preventative for migraine headaches that I have suffered from from 16 years. I have had pins and needles in my hands and feet as well as spontaneous crying fits since day 2 and Major aggression since yesterday. With normally an insurmountable amount of patience with my 1 year old son, I outright yelled at him last night. This is unacceptable. I have never felt such quick and sudden rage over nothing before, well, over anything before.
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  • Mucinex dm and advil congetstion
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  • Seizure disorder med problems (1 response)
    Velafaxine 150 mg. 1 per day.

    In process of switching from Topiramate 50 mg. 1 pill in morning & one at night (going off of this because of kidney stones) Was on this medication approximately 10 years.

    Lamotrigine 2 25mg pills in morning and 2 - 25 mg. pills at night.

    On the 3rd day of the 2nd week of switching I started the nightmares. I took a one hour nap and had a nightmare that seemed like it went on the entire time. Even if I slept for 20 minutes I had a dream or nightmare. I've sometimes been known to have vivid dreams but never this constant in my entire life. Also, very seldom do I have such terrible dreams. So many in one evening. They are an occasional thing, not an all night long thing.

    Also, I have sinus trouble occasionally. The same day the nightmares began I got a terrible headache behind my one eye and under my eye. I have no drainage yet anyway. Not sure if this is during the start up of this medicine, but if I had known it could cause trouble with sinus I would never have started it.

    I was put on this as a quick back up plan when the medicine we agreed upon - Levetireacetam made me feel drunk feeling and I had to be careful just walking around my homes and steps.
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More related studies for: Topamax, Fatigue

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