Review: could Topamax cause Kidney Failure?


Kidney failure is found among people who take Topamax, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Seroquel, and have Depression . We study 25,428 people who have side effects while taking Topamax from FDA and social media. Among them, 171 have Kidney failure. Find out below who they are, when they have Kidney failure and more.

You are not alone

Join a support group for people who take Topamax and have Kidney failure >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 27,293 users)

Kidney Failure

Kidney failure (loss of kidney function) has been reported by people with breathing difficulty, hypotension, renal failure acute, acute kidney failure, diarrhea (latest reports from 62,612 Kidney failure patients).

On Aug, 18, 2016

25,428 people reported to have side effects when taking Topamax.
Among them, 171 people (0.67%) have Kidney Failure

Number of reports submitted per year:

Could Topamax cause Kidney failure?

Time on Topamax when people have Kidney Failure *:

  • < 1 month: 50.0 %
  • 1 - 6 months: 12.5 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 12.5 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 12.5 %
  • 10+ years: 0.0 %

Gender of people who have Kidney Failure when taking Topamax *:

  • female: 82.04 %
  • male: 17.96 %

Age of people who have Kidney Failure when taking Topamax *:

  • 0-1: 0.77 %
  • 2-9: 2.31 %
  • 10-19: 3.85 %
  • 20-29: 5.38 %
  • 30-39: 12.31 %
  • 40-49: 23.85 %
  • 50-59: 22.31 %
  • 60+: 29.23 %

Severity if Kidney Failure when taking Topamax **:

  • least: 0.0 %
  • moderate: 0.0 %
  • severe: 100 %
  • most severe: 0.0 %

Top conditions involved for these people *:

  • Depression (23 people)
  • Pain (17 people)
  • Hypertension (14 people)
  • Multiple Sclerosis (13 people)
  • Bipolar Disorder (13 people)

Top co-used drugs for these people *:

  • Seroquel (31 people)
  • Lasix (25 people)
  • Protonix (22 people)
  • Prevacid (18 people)
  • Clonazepam (18 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Kidney failure when taking Topamax?

Browse all side effects of Topamax

a b c d e f g h i j k l m n o p q r s t u v w x y z

Drugs that are associated with Kidney failure

Kidney failure

Could your condition cause Kidney failure

Kidney failure

Can you answer these questions?

More questions for: Topamax, Kidney failure

You may be interested in these reviews

More reviews for: Topamax, Kidney failure

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.