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Review: could Topamax cause Low blood pressure (Hypotension)?





Summary: Low blood pressure is found among people who take Topamax, especially for people who are female, 50-59 old, have been taking the drug for < 1 month, also take medication Aspirin, and have Migraine.

We study 22,552 people who have side effects while taking Topamax from FDA and social media. Among them, 349 have Low blood pressure. Find out below who they are, when they have Low blood pressure and more.

You are not alone: join a mobile support group for people who take Topamax and have Low blood pressure >>>

Topamax

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,579 users)

Low blood pressure

Low blood pressure (abnormally low blood pressure) has been reported by people with high blood pressure, pain, multiple sclerosis, osteoporosis, depression.(latest reports from Low blood pressure 107,363 patients)

On Dec, 14, 2014: 22,552 people reported to have side effects when taking Topamax. Among them, 349 people (1.55%) have Low Blood Pressure.

Trend of Low blood pressure in Topamax reports

Time on Topamax when people have Low blood pressure * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ years
Low blood pressure42.31%30.77%0.00%11.54%15.38%0.00%0.00%

Gender of people who have Low blood pressure when taking Topamax * :

FemaleMale
Low blood pressure81.25%18.75%

Age of people who have Low blood pressure when taking Topamax * :

0-12-910-1920-2930-3940-4950-5960+
Low blood pressure0.62%2.17%3.73%9.32%16.77%21.12%26.71%19.57%

Severity of Low blood pressure when taking Topamax ** :

leastmoderateseveremost severe
Low blood pressure0.00%75.00%25.00%0.00%

How people recovered from Low blood pressure ** :

while on the drugafter off the drugnot yet
Low blood pressure50.00%0.00%50.00%

Top conditions involved for these people * :

  1. Migraine (48 people, 13.75%)
  2. Depression (42 people, 12.03%)
  3. Bipolar disorder (42 people, 12.03%)
  4. Convulsion (35 people, 10.03%)
  5. Multiple sclerosis (34 people, 9.74%)

Top co-used drugs for these people * :

  1. Aspirin (69 people, 19.77%)
  2. Klonopin (63 people, 18.05%)
  3. Neurontin (43 people, 12.32%)
  4. Protonix (40 people, 11.46%)
  5. Nexium (39 people, 11.17%)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you have Low Blood Pressure while taking Topamax?

You are not alone! Join a mobile support group:
- support group for people who take Topamax and have Low Blood Pressure
- support group for people who take Topamax
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Drugs in real world that are associated with:

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    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
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  • Can mrsa cause chronic intestinal pseudo obstruction?
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
    I never really recovered... The obstruction returned after 2 days and a portion of necrotic bowel was removed, then further fever and cellulitis then MRSA and deaths door.... Isolation in high dependency (intensive care) wound break down, ventilated and all related issues that come with that - chest infection, pneumonia, bed sores. Total time in hospital 8 months. Negative pressure dressing on laparotomy wound, colostomy, picc, 4 rounds of vancomycin, minor flirt with heart failure (just water related) an eventually everything healed. Had a large incisional hernia to repair and some corrective work to the horrific scarring but then the neuropathy started plus problems eating, spewing up after any solid food, more than a few forks, diarrhoea and sickness or constipation nausea and pain driving me mad, tried all manner of drugs, nerve blocks, physio, floating tank, acupuncture, opiates, non opiates, spinal cord stimulation, an now a consultant just had a 'eureka' moment and said were you treated with vancomycin when you had MRSA? If so I'm pretty sure you have chronic intestinal pseudo obstruction and is 90% sure but wants to take a muscle biopsy to be certain. I've had so much surgery and bad news in the last 10yrs I'm terrified of germs, hospital acquired bugs and anaesthetics, is there any other way? Or can I have this test done awake - conscious sedation? I had it before during spinal cord surgery so I know what's involved and it's better than GA as I know what's going on, who is doing what to me etc...
    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
    Reply
  • How to deal with low blood pressure caused by metformin
    I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope.

    I reduced Accupril until I am completely off Accupril. Still the BP was too low and I then reduced Metformin to one tab a day. The BP came back and gradually became too high , i.e., 150/92. I have to put Accupril back on at 5/2 mg then 5/4 mg then finally at 5/8 mg. This seems to be optimal but the Blood Sugar is at just above 100, sometimes 106. I wish to increase Metformin back to 2 a day but afraid Bp will become too low.

    Any input would be appreciated.
    Reply
  • Does topamax effect sexual desire and cause weight gain (1 answer)
    I have taken topamax for 10 years and have been gaining weight steadily every year. My doctor says the medication is not the reason because Topamax causes people to loose weight. I have also voiced my concerns to him that since I started taking this medication I have no desire for sex. He says this medication would not affect this. Please help so I can get him to change my medication.
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  • Omeprazole or pantoprazole?
    I take an oral contraceptive, Diane-35 ED, which is not in the list of drugs to choose from on this site.

    Recently, the medication I was taking for my stomach ulcer (Omeprazole) became unavailable in my country of residence and was replaced by Patoprazole. I started taking it yesterday morning and by midday today the side effects were unbearable. I am nauseous, have diarrhea, and a very severe headache. This didn't happen with Omeprazole. Do you think this is a drug interaction or is there some difference between the two that I am perhaps sensitive to?
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More questions for: Topamax, Low blood pressure

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    In process of switching from Topiramate 50 mg. 1 pill in morning & one at night (going off of this because of kidney stones) Was on this medication approximately 10 years.

    Lamotrigine 2 25mg pills in morning and 2 - 25 mg. pills at night.

    On the 3rd day of the 2nd week of switching I started the nightmares. I took a one hour nap and had a nightmare that seemed like it went on the entire time. Even if I slept for 20 minutes I had a dream or nightmare. I've sometimes been known to have vivid dreams but never this constant in my entire life. Also, very seldom do I have such terrible dreams. So many in one evening. They are an occasional thing, not an all night long thing.

    Also, I have sinus trouble occasionally. The same day the nightmares began I got a terrible headache behind my one eye and under my eye. I have no drainage yet anyway. Not sure if this is during the start up of this medicine, but if I had known it could cause trouble with sinus I would never have started it.

    I was put on this as a quick back up plan when the medicine we agreed upon - Levetireacetam made me feel drunk feeling and I had to be careful just walking around my homes and steps.
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  • Psychosis, weight loss and topamax (1 response)
    I had a brain hemorrhage in my occipital lobe. It left me with with a partial seizure disorder. The seizures would interrupt my ability to see. I was trying different anti-seizure medication and they all made me more tired and more depressed. My neurologist decided to try topamax. On topamax I began to feel more energetic and started losing weight. For the first time in years I woke up in the morning feeling zippy. I started feeling euphoric sometimes. I started to feel like I was glowing with life. I became so energetic I was like someone in a manic state. My temper got shorter and I began to hallucinate. I started to see angels and/or feel their presence. I live in a big city and there are a lot of people who are pretty mean here and I decided I wasn't going to let any of them push me around. I wasn't diplomatic anymore with anyone. Basically everyone thought I had gone crazy and I guess I had.
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