Review: could Topamax cause Multiple Sclerosis?


Multiple sclerosis is found among people who take Topamax, especially for people who are female, 40-49 old , have been taking the drug for 2 - 5 years, also take medication Rebif, and have Multiple sclerosis . We study 26,153 people who have side effects while taking Topamax from FDA and social media. Among them, 171 have Multiple sclerosis. Find out below who they are, when they have Multiple sclerosis and more.

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Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 27,293 users)

Multiple Sclerosis

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) has been reported by people with influenza like illness, urinary tract infection, weakness, gait disturbance, fatigue (latest reports from 278,805 Multiple sclerosis patients).

On Aug, 23, 2016

26,153 people reported to have side effects when taking Topamax.
Among them, 171 people (0.65%) have Multiple Sclerosis

Number of reports submitted per year:

Could Topamax cause Multiple sclerosis?

Time on Topamax when people have Multiple Sclerosis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 28.57 %
  • 6 - 12 months: 14.29 %
  • 1 - 2 years: 14.29 %
  • 2 - 5 years: 28.57 %
  • 5 - 10 years: 14.29 %
  • 10+ years: 0.0 %

Gender of people who have Multiple Sclerosis when taking Topamax *:

  • female: 89.22 %
  • male: 10.78 %

Age of people who have Multiple Sclerosis when taking Topamax *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.9 %
  • 20-29: 10.87 %
  • 30-39: 20.29 %
  • 40-49: 35.51 %
  • 50-59: 19.57 %
  • 60+: 10.87 %

Severity if Multiple Sclerosis when taking Topamax **:

  • least: 33.33 %
  • moderate: 33.33 %
  • severe: 33.33 %
  • most severe: 0.0 %

How people recovered from Multiple Sclerosis **:

  • while on drug: 0.0 %
  • after off the drug: 0.0 %
  • not yet: 100 %

Top conditions involved for these people *:

  • Multiple Sclerosis (91 people)
  • Migraine (21 people)
  • Pain (19 people)
  • Depression (12 people)
  • Relapsing-Remitting Multiple Sclerosis (9 people)

Top co-used drugs for these people *:

  • Rebif (39 people)
  • Avonex (36 people)
  • Baclofen (33 people)
  • Neurontin (30 people)
  • Copaxone (26 people)

* Approximation only. Some reports may have incomplete information.

** Reports from social media are used.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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